Mickey Mouse is a Disney comic book series that has a long-running history, first appearing in 1943 as part of the Four Color one-shot series. It received its own numbering system with issue #28, and after many iterations with various publishers, ended with #330 from IDW Publishing.

Four Color, also known as Four Color Comics and Dell Four Color, is an American comic book anthology series published by Dell Comics between 1939 and 1962. The title is a reference to the four basic colors used when printing comic books. The first 25 issues (1939–1942) are known as "series 1". In mid-1942, the numbering started over again, and "series 2" began. After the first hundred issues of the second series, Dell stopped putting the "Four Color Comics" designation on the books, but they continued the numbering system for twenty years.