The Greek Motorway 5 is a motorway in Greece. The motorway, commonly referred to as Ionia Odos or Ionia Motorway, starts at Ioannina and it follows the western coastline of mainland Greece down to the Gulf of Corinth. At Rio, it crosses the gulf via the Rio–Antirrio bridge and is connected with the A8 Motorway at an interchange near Patras. The future, currently under construction, Patras - Pyrgos motorway is typically part of the A5 Motorway and will eventually extend to Tsakona near Kalamata.

The Rio–Antirrio Bridge, officially the Charilaos Trikoupis Bridge, is one of the world's longest multi-span cable-stayed bridges and longest of the fully suspended type. It crosses the Gulf of Corinth near Patras, linking the town of Rio on the Peloponnese peninsula to Antirrio on mainland Greece by road. It opened one day before the Athens 2004 Summer Olympics, on 12 August 2004, and was used to transport the Olympic flame.