Nero Wolfe is an American drama television series based on the characters in Rex Stout's series of detective stories. The series aired on NBC from January 16 to August 25, 1981. William Conrad fills the role of the detective genius Nero Wolfe, and Lee Horsley is his assistant Archie Goodwin. Produced by Paramount Television, the series updates the world of Nero Wolfe to contemporary New York City and draws few of its stories from the Stout originals.

William Conrad was an American actor, producer, and director whose entertainment career spanned five decades in radio, film, and television, peaking in popularity when he starred in the detective series Cannon.