New York State Route 17 (NY 17) is a major state highway that extends for 397 miles (638.91 km) through the Southern Tier and Downstate regions of New York in the United States. It begins at the Pennsylvania state line in Mina and follows the Southern Tier Expressway east through Corning to Binghamton and the Quickway from Binghamton east to Woodbury, where it turns south to follow the Orange Turnpike to the New Jersey state line near Suffern, where it connects to New Jersey Route 17. From the Pennsylvania border to the village of Waverly and from Binghamton to Windsor, NY 17 is concurrent with Interstate 86 (I-86). Eventually, the entire east–west portion of NY 17 from the Pennsylvania border to Woodbury will become I-86 as projects to upgrade the route to Interstate Highway standards are completed.

The New York State Thruway is a system of controlled-access toll roads spanning 569.83 miles (917.05 km) within the U.S. state of New York. It is operated by the New York State Thruway Authority (NYSTA), a New York State public-benefit corporation. The 496.00-mile (798.23 km) mainline is a freeway that extends from the New York City line at Yonkers to the Pennsylvania state line at Ripley by way of I-87 and I-90 through Albany, Syracuse, and Buffalo. According to the International Bridge, Tunnel and Turnpike Association, the Thruway is the fifth-busiest toll road in the United States. The toll road is also a major route for long distance travelers linking the cities of Toronto and Buffalo with Boston and New York City.