Nicholson is a borough in Wyoming County, Pennsylvania. The population was 698 at the 2020 census.

Tunkhannock Creek Viaduct is a concrete deck arch bridge on the Nicholson Cutoff rail line segment of the Norfolk Southern Railway Sunbury Line that spans Tunkhannock Creek in Nicholson, Pennsylvania. Measuring 2,375 feet (724 m) long and towering 240 feet (73.15 m) when measured from the creek bed, it was the largest concrete structure in the world when completed in 1915 and still merited "the title of largest concrete bridge in America, if not the world" 50 years later.