Oleate hydratase

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oleate hydratase
EC number
CAS number 9073-51-2
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an oleate hydratase (EC is an enzyme that catalyzes the chemical reaction

(R)-10-hydroxystearate oleate + H2O

Hence, this enzyme has one substrate, (R)-10-hydroxystearate, and two products, oleate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (R)-10-hydroxystearate 10-hydro-lyase (oleate-forming). This enzyme is also called (R)-10-hydroxystearate 10-hydro-lyase.


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  • Gotouda H, Takatori T, Terazawa K, Nagao M, Tarao H (1988). "The mechanism of experimental adipocere formation: hydration and dehydrogenation in microbial synthesis of hydroxy and oxo fatty acids". Forensic Sci. Int. 37 (4): 249–57. doi:10.1016/0379-0738(88)90233-2. PMID 3410394. 
  • Jr; Torkelson, A; Kisic, A; Bednarczyk, DJ; Schroepfer Jr, GJ (1970). "Stereospecific hydration of the delta-9 double bond of oleic acid". J. Biol. Chem. 245 (15): 3790–7. PMID 5492948.