POMT2

From Wikipedia, the free encyclopedia
Jump to: navigation, search
POMT2
Identifiers
Aliases POMT2, LGMD2N, MDDGA2, MDDGB2, MDDGC2, protein O-mannosyltransferase 2
External IDs MGI: 2444430 HomoloGene: 5297 GeneCards: POMT2
Gene location (Human)
Chromosome 14 (human)
Chr. Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for POMT2
Genomic location for POMT2
Band 14q24.3 Start 77,274,956 bp[1]
End 77,320,884 bp[1]
RNA expression pattern
PBB GE POMT2 220632 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_013382

NM_153415

RefSeq (protein)

NP_037514

NP_700464

Location (UCSC) Chr 14: 77.27 – 77.32 Mb Chr 14: 87.11 – 87.15 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein O-mannosyl-transferase 2 is an enzyme that in humans is encoded by the POMT2 gene.[5][6][7]

Function[edit]

POMT2 encodes an integral membrane protein of the endoplasmic reticulum (ER) that shares significant sequence similarity with a family of protein O-mannosyltransferases of S. cerevisiae. For additional background information, see POMT1 (MIM 607423).[supplied by OMIM][7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000009830 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034126 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Fukuda S, Sumii M, Masuda Y, Takahashi M, Koike N, Teishima J, Yasumoto H, Itamoto T, Asahara T, Dohi K, Kamiya K (Feb 2001). "Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family". Biochem Biophys Res Commun. 280 (1): 407–14. doi:10.1006/bbrc.2000.4111. PMID 11162531. 
  6. ^ Willer T, Amselgruber W, Deutzmann R, Strahl S (Dec 2002). "Characterization of POMT2, a novel member of the PMT protein O-mannosyltransferase family specifically localized to the acrosome of mammalian spermatids". Glycobiology. 12 (11): 771–83. doi:10.1093/glycob/cwf086. PMID 12460945. 
  7. ^ a b "Entrez Gene: POMT2 protein-O-mannosyltransferase 2". 

Further reading[edit]

External links[edit]