POU4F2

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POU4F2
Identifiers
AliasesPOU4F2, BRN3.2, BRN3B, Brn-3b, POU class 4 homeobox 2
External IDsMGI: 102524 HomoloGene: 20959 GeneCards: POU4F2
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for POU4F2
Genomic location for POU4F2
Band4q31.22Start146,638,893 bp[1]
End146,642,474 bp[1]
RNA expression pattern
PBB GE POU4F2 207725 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004575

NM_138944

RefSeq (protein)

NP_004566

NP_620394

Location (UCSC)Chr 4: 146.64 – 146.64 MbChr 8: 78.43 – 78.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.[5][6]

Function[edit]

POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.[supplied by OMIM][6]

Interactions[edit]

POU4F2 has been shown to interact with Estrogen receptor alpha.[7]

See also[edit]

References[edit]

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.