Palmer is a city in and the borough seat of the Matanuska-Susitna Borough, Alaska, United States, located 42 miles (68 km) northeast of Anchorage on the Glenn Highway in the Matanuska Valley. It is the ninth-largest city in Alaska, and forms part of the Anchorage Metropolitan Statistical Area. As of the 2020 census, the population of the city is 5,888, down from 5,937 in 2010.

Matanuska-Susitna Borough is a borough located in the U.S. state of Alaska. Its borough seat is Palmer, and the largest community is the census-designated place of Knik-Fairview. As of the 2020 census, the borough's population was 107,801.