Pentalenolactone D synthase

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Pentalenolactone D synthase
Identifiers
EC number 1.14.13.170
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Pentalenolactone D synthase (EC 1.14.13.170, penE (gene), pntE (gene)) is an enzyme with systematic name 1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (pentalenolactone-D forming).[1] This enzyme catalyses the following chemical reaction

1-deoxy-11-oxopentalenate + NADPH + H+ + O2 pentalenolactone D + NADP+ + H2O

Pentalenolactone D synthase is a FAD-dependent oxygenase.

References[edit]

  1. ^ Seo, M.J.; Zhu, D.; Endo, S.; Ikeda, H.; Cane, D.E. (2011). "Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone". Biochemistry. 50 (10): 1739–1754. doi:10.1021/bi1019786. PMC 3051010. PMID 21250661.

External links[edit]