Pentarane A

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Pentarane A
Pentarane A.svg
Clinical data
Synonyms D'6-Pentarane; Pregna-D'6-pentarane; 16α,17α-Cyclohexanoprogesterone; 16α,17α-Tetramethylenepregn-4-ene-3,20-dione; 17α-Acetyl-16β,24-cyclo-21-norchol-4-en-3-one
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C25H36O2
Molar mass 368.56 g·mol−1
3D model (JSmol)

Pentarane A, also known as D'6-pentarane or pregna-D'6-pentarane, as well as 16α,17α-cyclohexanoprogesterone, 16α,17α-tetramethylenepregn-4-ene-3,20-dione, or 17α-acetyl-16β,24-cyclo-21-norchol-4-en-3-one, is a steroidal progestin that was developed by the Zelinskii Institute of Organic Chemistry of the Russian Academy of Sciences and was never marketed.[1][2] The 6α-methylated analogue of pentarane A is known as mecigestone or as pentarane B.[2]

See also[edit]

References[edit]

  1. ^ Kamernitzky AV, Levina IS, Kulikova LE, Ignatov VN, Korkhov VV, Nikitina GV, Terekhina AI (1982). "Pregna-D'-pentaranes - a new class of active gestagenes". J. Steroid Biochem. 16 (1): 61–7. PMID 7062740. 
  2. ^ a b Bhakta, Amrita; Herman, Michelle; Levina, Inna S.; Moudgil, V. K. (1993). "Interaction of cycloalkanoprogesterones with mammalian progesterone receptor: binding of pregna-D'-pentaranes in the calf uterine cytosol". Molecular and Cellular Biochemistry. 125 (2): 153–161. doi:10.1007/BF00936444. ISSN 0300-8177.