Peter Guralnick is an American music critic and screenwriter. He specializes in the history of early rock and roll and has written on Elvis Presley, Sam Phillips, Sam Cooke. Guralnick graduated from Boston University in 1971 with a master's degree in creative writing, he began writing books about the history of rock'n'roll, country music, soul music. Guralnick's first two books, Almost Grown and Mister Downchild, were collections of short stories published by the Larry Stark Press, a small press in Cambridge, devoted to stories and poems. Mona Dickson, writing in MIT's The Tech gave Almost Grown a favorable review, his two-volume biography of Elvis Presley, Last Train to Memphis in 1994, followed by Careless Love in 1999, placed the story of Presley's career into a rise and fall arc. Encompassing more than 1,300 pages, the work was an in-depth, scholarly examination of Presley's life and music. Guralnick wrote about Presley in The Rolling Stone Illustrated History of Rock & Roll, in its first edition, in 1976.

He contributed the complete text for the 240-page hardcover book accompanying the 2010 30-disc CD boxed set, The Complete Elvis Presley Masters. In contrast to contemporaries such as Lester Bangs, Ian Penman and Nick Tosches, whose music writings are marked by idiosyncratic, self-referential and personal styles, Guralnick's writing is characterized by a colloquial approach, clean and understated by comparison, he has been called "the dean of rock'n' roll storytellers". Guralnick wrote the 727-page biography of influential record producer Sam Phillips entitled Sam Phillips: The Man Who Invented Rock'n' Roll, he penned the script for A&E's documentary of the same name, narrated by Billy Bob Thornton. On October 21, 2016, it was announced that Leonardo DiCaprio will portray Sam Phillips in the forthcoming film based on Guralnick's book. Guralnick scripted Sam Cooke – Legend, narrated by Jeffrey Wright, he has written liner notes for albums including Charlie Rich's last album Pictures and Paintings and the last three Jerry Lee Lewis albums Last Man Standing, Mean Old Man and Rock and Roll Time.

The Peter Guralnick Collection is located in the Southern Folklife Collection of the Wilson Library of the University of North Carolina at Chapel Hill. Peter Guralnick's parents were Walter Guralnick, DMD, who helped to establish dental insurance in Massachusetts through Delta Dental, Betty Marson Guralnick. In 1971, he succeeded his grandfather as director of an athletic camp for Camp Alton, it was located on Lake Winnipesaukee in New Hampshire. The camp closed in 1992, he has been married for over 45 years to Alexandra. They have a son and daughter and Nina. Peter Guralnick. Grown. Cambridge, Massachusetts: Larry Stark Press. ——. Mister Downchild. Cambridge, Massachusetts: Larry Stark Press. ——. Feel Like Going Home: Portraits in Blues and Rock'n' Roll. ISBN 0-87690-046-5. Reprinted 1999. ISBN 0-316-33272-0 ——. Lost Highway: Journeys & Arrivals of American Musicians. ISBN 0-316-33274-7. ——. The Listener's Guide to The Blues. New York: Facts on File. ——. Sweet Soul Music: Rhythm and Blues and the Southern Dream of Freedom.

ISBN 0-316-33273-9. ——. Nighthawk Blues: A Novel. Thunder's Mouth Press. ISBN 0-938410-64-4. ——. Searching for Robert Johnson. ISBN 0-452-27949-6. ——. Last Train to Memphis: The Rise of Elvis Presley. ISBN 0-316-33225-9. ——. Careless Love: The Unmaking of Elvis Presley. ISBN 0-316-33297-6. ——. Elvis Day by Day: The Definitive Record of His Life and Music. ISBN 0-345-42089-6. ——. Dream Boogie: The Triumph of Sam Cooke. Little, Brown. ISBN 0-316-37794-5. ——. Sam Phillips: The Man Who Invented Rock'n'Roll. Little, Brown. "An Interview with Peter Guralnick" by Griffin Ondaatje and Craig Proctor, Brick: A Literary Journal, Issue 62, Spring 1999. "Caught in a Trap" at the Wayback Machine. Peter S. Sholtes interviews Peter Guralnick. City Pages Media, January 13, 1999. Archived from the original, 2001-05-26. Music Historian Peter Guralnick — Serious Jibber Jabber with Conan O'Brien discuss PG's 1994 book Last Train to Memphis: The Rise of Elvis Presley For Guralnick, birthday bash starts the Elvis bandwagon rolling By Clarissa Sansone, March 2002.

Country Standard Time. Guralnick at SXSW. Authors: Peter Guralnick at the Wayback Machine. Time Warner Bookmark. Archived from the original 2002-02-12. "Elvis Presley: Baby What You Want Me To Do". By Robert Baird, May 2000. Stereophile. Camp Alton - Official website Peter Guralnick Collection, Southern Folklife Collection, Wilson Library, University of North Carolina at Chapel Hill

FABP1 is a human gene coding for the protein product FABP1. It is frequently known as liver-type fatty acid-binding protein. FABP1 is expressed in the liver where it is involved in the binding and metabolism of long-chain fatty acids, phytocannabinoids and other hydrophobic molecules. Altered expression of the protein has been linked to metabolic conditions including obesity; the fatty acid-binding proteins were discovered in 1972 with experiments using 14C labelled oleate to identify the presence of a soluble fatty acid carrier in the enterocyte responsible for intestinal absorption of. Since ten members of the FABP family have been identified on the human genome. Nine are well established with a discovered tenth; each FABP corresponds to particular organs/tissue around the body where they play a role in fatty-acid uptake and metabolism. The human FABP1 gene is located on the short arm of chromosome 2 from base pair 88,122,982 to base pair 88,128,131. FABP1 has been found to have a unique structure compared to other members of the FABP family, allowing it to bind multiple ligands simultaneously.

It has a larger solvent-accessible core compared to other FABPs allowing more diverse substrate binding. The “portal hypothesis” has been proposed to explain the binding process of FABPs, it has been suggested that fatty acids enter the solvent-accessible area of the protein through a dynamic region consisting of α-helix II and turns between βC-βD and βE-βF loops. The fatty acid is bound in the protein cavity for transport; the FABPs are a family of small conserved cytoplasmic proteins involved in the binding of LCFAs. FABP1 is expressed abundantly in the human liver where it accounts for 7-11% of the total cytosolic protein, can be found in the intestine, pancreas stomach and lung. FABP1 is unique in the wider range of other hydrophobic ligands it can bind including bilirubin, bile acids and fatty acyl CoA, it has been proposed that FABP1 plays a significant role in preventing cytotoxicity by binding heme, fatty acids and other molecules that are toxic when unbound. On exon 3 of the human FABP1 gene an Thr to Ala substitution has been identified leading to a T94A missense mutation.

Carriers of this particular single nucleotide polymorphism exhibit higher baseline plasma-free fatty acid levels, lower BMI and a smaller waist circumference. The T94A mutant has been associated with metabolic syndrome conditions, cardiovascular disease and T2DM. Studies with mice to determine the effect of suppressing the FABP1 gene have been performed; when provided with high-fat or high-cholesterol based diets those with suppressed FABP1 expression demonstrated a significant impact on metabolic regulation and weight gain. A study in Chinese young adults indicates a strong relationship between serum FABP1 levels and lipid profile, body measurements and homeostatic parameters. Increased BMI and insulin resistance in subjects demonstrated higher serum FABP1 with a particular correlation in subjects with central adiposity; this elevation is suggested to occur as a compensatory up-regulation of the protein in an attempt to counter the high metabolic stress associated with obesity. Alternately obesity may in fact lead the human body to develop resistance to the actions of FABP1 leading to the compensatory up-regulation.

Evaluation of increased levels of urinary and serum FABP1 have shown to be effective markers in the detection of intestinal ischaemia, progressive end-stage renal failure and ischaemic damage caused by renal transplantation or cardiac bypass surgery

In 2018, U. S. states proposed or are expected to propose cannabis reform legislation for medical marijuana and non-medical adult use. State-level legalization remains at odds with cannabis' status as a Schedule I narcotic under the Controlled Substances Act at the Federal level, the Cannabis policy of the Donald Trump administration appeared to become more hostile than that of the previous administration, with the early January rescission of the Cole Memorandum. States expected to be most to propose legislation to legalize include Michigan, New Hampshire, New Jersey, Rhode Island. Other possible full legalization states include Connecticut and Ohio. In the House of Representatives, Democratic Representatives Barbara Lee of California and Representative Ro Khanna, of the same state, introduced the Marijuana Justice Act, the counterpart of a Senate Bill 1689, introduced in 2017 by Senator Cory Booker. A bipartisan bill, the Sensible Enforcement Of Cannabis Act, was introduced in February. In late March, Senate Majority Leader Mitch McConnell announced he would introduce the Hemp Farming Act of 2018.

It would expand the experimental hemp production allowed under the 2014 farm bill, removing hemp from Schedule I controlled substances and making it an ordinary agricultural commodity. He introduced the bill on the Senate floor on April 12. On April 11, President Donald Trump told Senator Cory Gardner of Colorado that he would "support congressional efforts to protect states that have legalized marijuana". A bill to resolve the state-Federal conflict was still "a work in progress" but seemed to a Colorado cannabis industry group be implicit in Gardner's comments afterwards. California Senator Dianne Feinstein made a surprising reversal of her prior stance against state or federal legalization in May and said she was "open to supporting" the Gardner bill. Gardner and Senator Elizabeth Warren introduced the STATES Act in June to apply Federal prohibition only in states that did not have state-level legalization. In summary, Vermont passed legislation legalizing cannabis statewide in January, the first time legalization occurred via legislature, not initiative.

Utah legalized medical cannabis without THC restrictions for some patients in March. Industrial hemp laws were passed in Alaska and Oklahoma in April, a New Mexico Supreme Court decision ordered the promulgation of a 2017 hemp bill. Oklahoma legalized medical cannabis in June. Senate Bill 6, allowing industrial hemp farming, was passed unanimously by both chambers of the state legislature, with passage in the House occurring on February 19, 2018, it was signed into law by the governor on April 13. An initiative to legalize hemp, defined as cannabis with less than 0.4% THC, was listed by the Secretary of State as a potential November, 2018 ballot measure. House Bill 1295 passed both houses of the state legislature, by April, it would "regulate hemp like any other food ingredient". A provision of the bill prohibits pharmaceutical companies from "interfering" with distribution or sale of occurring hemp products. In April, HB 5394, a bill to "require multiple state agencies to coordinate and develop a plan to legalize and regulate cannabis sales by October 1" was referred from the Appropriations Committee to the state General Assembly.

This was the first time. State senator Curt Thompson introduced legislation to legalize cannabis, in January. Atlanta had decriminalized the substance in 2017. Voters in Cook County answered 68% "yes" on a March referendum on statewide cannabis legalization. Earlier in March, the state senate had voted 73-13 to approve a bill sponsored by Bill Cunningham, presenting a statewide referendum on legalization in November. SB316 and HB2353, which would create a regulated legalized adult-use system in Illinois, were introduced in 2017 and were still under consideration by the legislature in 2018. A hemp bill, SB 2298, passed the state Senate unanimously on April 24, it would remove industrial hemp from the state's legal definition of a drug, put it under regulation by the state Department of Agriculture. The bill passed the state House of Representatives 106-3 on May 25; the Iowa state Senate passed File 2398, the "Iowa Industrial Hemp Act", 49-0 on April 4. In March, Kansas Senate Bill 263, legalizing a hemp research and production pilot under the state's Department of Agriculture in accordance with the Federal 2014 Farm Bill, cleared the state House of Representatives 123 to 1 and the state Senate 36 to 3.

The bill was signed into law by the governor on April 20. Although the legalization of cannabis in Massachusetts for recreational use was passed in a 2016 ballot, the purchase of recreation cannabis is still not legal in the state; the Massachusetts state legislature, who opposed the ballot question, have delayed the opening of any recreational dispensaries through additional regulatory means. As of January, 2018 a group had submitted over 300,000 signatures for the 2018 Michigan Marijuana Legalization Initiative pending certification by the state for the 2018 general election ballot; the state certified the initiative on April 26. Proposal 1 was approved by voters on November 6, the Secretary of State certified the election returns as of November 26, as such, the proposal must become law in Michigan by no than December 6. SB 547 and HB 2034 were introduced to legalize hemp farming; the senate bill passed on March 15. Several versions of "Missouri Cannabis and Cannabis Hemp Legalization Initiative" were proposed to amend the Missouri state constitution.

Initiative 2018-134 would allow prescription of cannabis by

Arzier-Le Muids is a municipality in the district of Nyon in the canton of Vaud in Switzerland. The first mention of Arzier was in 1306 as the village Argie. Throughout the Middle Ages Arzier's name is seen in documents as Arsie and Arsier. Le Muids is first mentioned as a barn in 1250. Settlers were granted land in Arzier by the abbey of Oujon in 1304. In 1536 control of the region, of all of the lands of the abbey were lost to a conquering duke from Bern; this duke wasn't appreciated because he did not let each village govern itself, causing numerous problems and much discontent. Less than a century had past before the Brennards and Rafi lost their patience and stopped farming altogether, descending into extreme poverty; as time went by and the land went to waste, the regional government decided to take drastic measures, in 1664, granted Arzier political independence. The village still had to pay a tax to Nyon; this is seen as the beginning of Arzier's prosperity. In the early days of independence, the local council was composed of 8 members, each elected for life terms.

Half came from the other half from Le Muids. Today the political structure is much more complex, with the executive branch being made up of a mayor, a vice-mayor and three ministers, the legislative being made up of a council of a president, two vice presidents and 52 general members. Arzier has an area, as of 2009, of 51.9 square kilometers. Of this area, 13.11 km2 or 25.3% is used for agricultural purposes, while 36.86 km2 or 71.0% is forested. Of the rest of the land, 1.61 km2 or 3.1% is settled, 0.01 km2 or 0.0% is either rivers or lakes and 0.26 km2 or 0.5% is unproductive land. Of the built up area and buildings made up 1.8% and transportation infrastructure made up 1.1%. Out of the forested land, 67.1% of the total land area is forested and 3.9% is covered with orchards or small clusters of trees. Of the agricultural land, 3.1% is used for growing crops and 1.6% is pastures and 20.4% is used for alpine pastures. All the water in the municipality is flowing water; the municipality was part of the old Nyon District until it was dissolved on 31 August 2006, Arzier became part of the new district of Nyon.

The official name of the municipality was "Arzier", has been changed to "Arzier-Le Muids" in September 2013. The name is a mix of Arzier and Le Muids and the hamlet of Montant and La Chèvrerie. Le Muids is a small village which, due to its small size and proximity to Arzier is part of the same municipality as its larger neighbor. Arzier natives are called "Brennards" because the village experienced a severe fire in its early days. Residents of Le Muids are called "Rafi." The blazon of the municipal coat of arms is Per pale Gules and Azure, overall a branch Vert with three leaves and two roses Argent, from dexter and sinister a cloud of the last from each issuing hand of the same clothed Or shaking the other one. Arzier has a population of 2,698; as of 2008, 25.6% of the population are resident foreign nationals. Over the last 10 years the population has changed at a rate of 24.4%. It has changed at a rate of 6.5 % due to births and deaths. Most of the population speaks French, with German being second most English being third.

There are 1 person who speaks Romansh. The age distribution, as of 2009, in Arzier is. Of the adult population, 169 people or 7.8 % of the population are between 29 years old. 259 people or 11.9% are between 30 and 39, 406 people or 18.6% are between 40 and 49, 327 people or 15.0% are between 50 and 59. The senior population distribution is 237 people or 10.9% of the population are between 60 and 69 years old, 83 people or 3.8% are between 70 and 79, there are 49 people or 2.2% who are between 80 and 89, there are 16 people or 0.7% who are 90 and older. As of 2000, there were 758 people who never married in the municipality. There were 97 individuals who are divorced; as of 2000, there were 655 private households in the municipality, an average of 2.6 persons per household. There were 158 households that consist of only one person and 62 households with five or more people. Out of a total of 679 households that answered this question, 23.3% were households made up of just one person and there were 3 adults who lived with their parents.

Of the rest of the households, there are 188 married couples without children, 242 married couples with children There were 49 single parents with a child or children. There were 15 households that were made up of unrelated people and 24 households that were made up of some sort of institution or another collective housing. In 2000 there were 518 single family homes out of a total of 633 inhabited buildings. There were 64 multi-family buildings, along with 33 multi-purpose buildings that were used for housing and 18 other use buildings that had some housing. Of the single family homes 28 were built before 1919, while 62 were built between 1990 and 2000; the greatest number of single family homes were built between 1971 and 1980. The most multi-family homes were

Originators of the Northern Darkness is a tribute album to the Norwegian black metal band Mayhem, with contributions from some of the leading bands in the black metal and death metal scene. All the songs were recorded between 1998 and 2000 in various locations, the album was released on CD in 2001 by Avantgarde Music. In addition to the regular CD, a limited edition CD in black leather was released; the album was re-released on digipack CD in 2007 by Peaceville. "From the Dark Past" – Immortal – 04:40 Originally appeared on De Mysteriis Dom Sathanas. "Pagan Fears" – Dark Funeral – 06:34 Originally appeared on De Mysteriis Dom Sathanas. "Freezing Moon" – Vader – 05:45 Originally appeared on De Mysteriis Dom Sathanas. "Funeral Fog" – Emperor – 05:13 Originally appeared on De Mysteriis Dom Sathanas. "Carnage" – Behemoth – 04:07 Originally appeared on Pure Fucking Armageddon. "De Mysteriis Dom Sathanas" – Limbonic Art – 06:51 Originally appeared on De Mysteriis Dom Sathanas. "Buried by Time and Dust" – Keep of Kalessin – 03:34 Originally appeared on De Mysteriis Dom Sathanas.

"Life Eternal" – Gorgoroth – 04:45 Originally appeared on De Mysteriis Dom Sathanas. "Ghoul" – Carpathian Forest – 03:41 Originally appeared on Pure Fucking Armageddon. "I Am Thy Labyrinth" – Seth – 05:29 Originally appeared on Wolf's Lair Abyss. "Cursed in Eternity" – Gehenna – 04:58 Originally appeared on De Mysteriis Dom Sathanas. "Deathcrush" – Absu – 06:52 Originally appeared on Deathcrush. Gorgoroth's line-up on track 8 consisted of Gaahl on vocals and Tormentor on rhythm guitars, T-Reaper on lead guitar and bass, Vrolok on drums. Seth's track is mistitled as the original Mayhem version is titled "I am thy labyrinth", it is mistitled on Osmose Productions' "World Domination IV" compilation on which it appears too

The discography of American electronica project Owl City consists of six studio albums, seven extended plays, twenty singles, twelve music videos. Owl City issued its debut release, the extended play Of June, in September 2007, his debut studio album Maybe I'm Dreaming followed in December 2008, peaking at number 13 on the Dance/Electronic Albums chart. Following the success of Of June and Maybe I'm Dreaming, Young signed to Universal Republic Records in late 2008, his second studio album and major-label debut, Ocean Eyes, was released in July 2009. "Fireflies", the album's lead single, became an international success, peaking at number one on the US Billboard Hot 100 and becoming a top ten hit in several other countries. Fueled by success of "Fireflies", Ocean Eyes peaked at number eight on the US Billboard 200 and was certified platinum by the Recording Industry Association of America. An additional three singles were released from the album: "Vanilla Twilight", "Hello Seattle" and "Umbrella Beach".

Owl City's third studio album All Things Bright and Beautiful was released in June 2011, peaking at number six on the Billboard 200 and selling 143,000 copies. The album produced six singles, with "Alligator Sky" and "Lonely Lullaby" managing to chart on the US Billboard Bubbling Under Hot 100 Singles chart. "Good Time", a collaboration with Canadian recording artist Carly Rae Jepsen, peaked at number eight on the Billboard Hot 100 and became a top ten chart hit in countries such as Australia and the United Kingdom. Owl City released his fourth studio album The Midsummer Station in August 2012. On July 10, 2015, Owl City released his fifth album, titled Mobile Orchestra, spawning the singles "You're Not Alone", "Verge" and "Unbelievable". Owl City's sixth studio album, was released on June 1, 2018. Official website Owl City at AllMusic Owl City discography at Discogs Owl City discography at MusicBrainz