Phytoene desaturase (3,4-didehydrolycopene-forming)

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Phytoene desaturase (3,4-didehydrolycopene-forming)
Identifiers
EC number 1.3.99.30
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Phytoene desaturase (3,4-didehydrolycopene-forming) (EC 1.3.99.30, 5-step phytoene desaturase, five-step phytoene desaturase, phytoene desaturase (ambiguous), Al-1) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction

15-cis-phytoene + 5 acceptor all-trans-3,4-didehydrolycopene + 5 reduced acceptor (overall reaction)
(1a) 15-cis-phytoene + acceptor all-trans-phytofluene + reduced acceptor
(1b) all-trans-phytofluene + acceptor all-trans-zeta-carotene + reduced acceptor
(1c) all-trans-zeta-carotene + acceptor all-trans-neurosporene + reduced acceptor
(1d) all-trans-neurosporene + acceptor all-trans-lycopene + reduced acceptor
(1e) all-trans-lycopene + acceptor all-trans-3,4-didehydrolycopene + reduced acceptor

This enzyme is involved in carotenoid biosynthesis.

References[edit]

  1. ^ Hausmann, A.; Sandmann, G. (2000). "A single five-step desaturase is involved in the carotenoid biosynthesis pathway to β-carotene and torulene in Neurospora crassa". Fungal Genet. Biol. 30 (2): 147–153. doi:10.1006/fgbi.2000.1212. PMID 11017770.
  2. ^ Estrada, A.F.; Maier, D.; Scherzinger, D.; Avalos, J.; Al-Babili, S. (2008). "Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation". Fungal Genet. Biol. 45: 1497–1505. doi:10.1016/j.fgb.2008.09.001. PMID 18812228.

External links[edit]