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Mason-Pfizer monkey virus

Mason-Pfizer monkey virus Simian retrovirus, is a species of retroviruses that infect and cause a fatal immune deficiency in Asian macaques. This virus appears sporadically in captive macaques at breeding facilities which expected as the natural host, but prevalence of this virus in feral macaques remain unknown. SRV was transmitted by virus-containing body fluids, via biting or scratching. Contaminated instrument or equipment can spread this virus among animals; some clinical and pathological symptoms of SRV-infected macaques are diarrhea, weight loss, lymphadenopathy, neutropenia, neoplastic diseases. To prevent the infection of this virus, two vaccinations have been developed; those two effective vaccinations are formalin-inactivated whole SRV-1 vaccine and recombinant vaccine expressing SRV envelope glycoprotein gp70 and gp 22. Until 2006, six types of SRVs have been identified; the original prototype of SRV is Mason-Pfizer monkey virus, which derived from breast tumor tissue of a rhesus macaque in 1970.

This prototype virus now belongs to SRV serotype-3 group. SRV-1 serotype was identified in early 1980s in rhesus macaque, M. cyclopis, M. fascicularis at National Primate Research Center and New England. The SRV serotype-2 was found in endemic infections of pig-tailed monkey, cynomolgus macaques, Japanese macaque, at Washington NPRC, in rhesus and Celebes black macaques at Oregon NPRC. SRV-3 is present at Wisconsin Primate Center, while SRV-4 and SRV-5 have been identified at University of California and Beijing Primate Center. In 2010, a Japanese research group reported two SRV isolates from seropositive cynomolgus macaques and tentatively designated them as SRV/D-Tsukuba. In 2011, players of Foldit helped to decipher the crystal structure of the Mason-Pfizer monkey virus retroviral protease. While the puzzle was available to play for a period of three weeks, players produced an accurate 3D model of the enzyme in just ten days, used to solve the structure with molecular replacement; the problem of how to configure the structure of the enzyme had stumped scientists for 15 years.

SRV is an enveloped RNA retrovirus with icosahedral capsid. The extracellular mature particles are about 125 nm in diameter, while the nucleoid and core shell are central cylindrical structures separated by a space of about 8-10 nm; this virus utilize a glycoprotein-lipid bilayer from host cell membrane to perform budding process in the end of its replication cycles. The SRV genome contains four genes: 5'-gag-prt-pol-env-3'. Gag encodes group-specific antigen, Prt for protease, Pol responsible for RNA-dependent DNA polimerase region, Env encodes the envelope glycoprotein. Same with all restroviruses, SRV is able to transcribe its own RNA genome into double-stranded DNA by using reverse transcriptase enzyme. "Simian retrovirus 1". NCBI Taxonomy Browser. 11942

Mineraloid

A mineraloid is a occurring mineral-like substance that does not demonstrate crystallinity. Mineraloids possess chemical compositions that vary beyond the accepted ranges for specific minerals. For example, obsidian is an amorphous glass and not a crystal. Jet is derived from decaying wood under extreme pressure. Opal is another mineraloid because of its non-crystalline nature. Pearl, considered by some to be a mineral because of the presence of calcium carbonate crystals within its structure, would be better considered a mineraloid because the crystals are bonded by an organic material, there is no definite proportion of the components. Amber, non-crystalline structure, organic Chlorophaeite Deweylite, a mixture of serpentine and talc or stevensite Ebonite, vulcanized natural or synthetic rubber; the Mineraloids Class. Amethyst Galleries

Kuru Kuru Kururin

Kuru Kuru Kururin is a puzzle video game developed by Eighting and published by Nintendo for the Game Boy Advance handheld video game console. It was released in Japan on March 21, 2001 and in Europe and Australia on June 22, 2001 as a launch title. North America saw the title for the first time on February 11, 2016 via the Wii U's Virtual Console service. Kuru Kuru Kururin is the first title in the Kururin series and was followed by two Japan-only sequels, Kururin Paradise and Kururin Squash! The player controls a spinning stick called the Helirin, or the Helicopter in the European localization, must maneuver it through a series of mazes without touching the walls; the player controls the direction and speed of movement, but the task is made difficult as the stick rotates continuously. The Helirin can move faster by holding down any of the two face buttons, faster by holding down both. There are bonuses to collect, record times to beat, a gold star for completing the level without any accidents.

The game features multiplayer support, which enables four players to participate in the action using a single cartridge. Kuru Kuru Kururin was released in Europe, but not in North America. However, as the Game Boy Advance has no regional lockout, a North American Game Boy Advance can be used to play either the Japanese or European version of the game; the menus in the Japanese version are simple enough that they are navigable by a player who knows no Japanese. The game starts with simple training levels, in which players are told how to play and how to get around the first corners. After that, there are three levels in each stage, which get longer; the obstacles and the look of the levels vary between stages. Beginners can play the levels on Easy mode. There is a mode called Challenge mode, a collection of smaller levels involving only one or two corners or objects to dodge; the story begins when Kururin's brothers and sisters go missing, it is up to him to find them. Kururin is unsure that he is up to the task because he has never left his home world before.

Being the adventurous and helpful fellow he is, Kururin agrees to rescue his lost family. Teacher Hare trains Kururin in the art of controlling the Helirin, a stick-shaped helicopter that has a slow-spinning propeller. Piloting the Helirin through the different worlds will be a difficult task, but using Teacher Hare's valuable lessons, Kururin bravely sets out on his adventure to rescue his lost family. Kuru Kuru Kururin was developed by the Japanese company Eighting and first announced at the Nintendo Space World 2000. Kuru Kuru Kururin received positive reviews from critics, it was praised for its addictive gameplay. Eurogamer rated the game a score of 9 out of 10 points; the reviewer lauded the game's learning curve and stated that there would be no other puzzle game on the Game Boy Advance at the time that can "rival Kuru Kuru Kururin for its sheer addictiveness and fun-value." Nintendo World Report known as Planet GameCube, gave Kuru Kuru Kururin the same score as Eurogamer and declared that it is "simple enough that anyone can pick this game up and play."

The reviewer praised the game's multiplayer mode, which he described as "an absolute blast," as well as its lasting appeal, but commented that the "cutesy" characters and music would be a turn-off for "a lot of people." Jeff Gerstmann of GameSpot rated Kuru Kuru Kururin 7.1 out of 10 and described its graphics as "simple but effective." He stated that the game is "excellent at filling up small periods of free time with its short, level-based nature." Computer and Video Games was less impressed by the game, rating it 5 out of 10. The reviewer declared the game to be "extremely frustrating" and stated that it lacks "the perfect simplicity" of other puzzle games such as Mr. Driller and Tetris. Nonetheless, he commented that the novel gameplay of Kuru Kuru Kururin "will find many fans" and that the multiplayer mode is "unexpectedly brilliant." The first sequel entitled Kururin Paradise came out in 2002 for the Game Boy Advance. It was released in Japan only though Kururin Paradise was showcased at E3 2002, the first time a Kururin game had been announced for the American market.

Another sequel was released only in Japan for the Nintendo GameCube in 2004, entitled Kururin Squash!, which became the only title of the series to feature 3D computer graphics, as well as to appear on a home console. Several references to the Kururin series are made in the Super Smash Bros. series. The Helirin makes a cameo appearance as a trophy in Super Smash Bros. Melee, but is incorrectly referred to as "Heririn" in the American version; the Helirin appears in Super Smash Bros. Brawl as an Assist Trophy. Unlike most Assist Trophies, it doesn't attack, but it becomes part of the stage, can be used as a platform or a wall. Several other things in the Kururin series appear as Stickers in the game. Kuru Kuru Kururin at Nintendo.com.au Official Japanese website Official Japanese SpaceWorld 2000 webpage Kuru Kuru Kururin at MobyGames Kururin series at Hardcore Gaming 101

Anne of Green Gables: The Animated Series

Anne of Green Gables: The Animated Series is a Canadian animated television series produced by Sullivan Entertainment and developed by writer/director/producer Kevin Sullivan, based on the 1908 novel Anne of Green Gables by L. M. Montgomery. One season of the series was produced, with 26 episodes airing from 2001 to 2002; the series was developed for PBS. The show aired in reruns on Qubo from May 13, 2013, until December 25, 2016; each episode contained an educational aspect, with a problem for one or more of the show's characters to face and solve. In conjunction with these problems, PBS "Ready-to-Learn" guides were created for teachers in America to use in classrooms. Bryn McAuleyAnne Shirley - a smart and imaginative redheaded orphan girl, adopted by the aging Cuthbert siblings, she appears in every episode of the show. In the opening sequence, Anne had a magical ability to fly. Wayne Robson – Matthew Cuthbert - a quiet and kind bachelor farmer, Marilla's older brother and Anne's adoptive father.

Emily Hampshire – Diana Barry - Anne's best friend, known for her jet-black hair and sunny disposition. Ali MukaddamGilbert Blythe - Anne's friend who competes with her academically. Dalene Irvine – Felicity King - a classmate of Anne and company, jealous of her and seeks to embarrass her often; however and Anne are still friends. Kyle Fairlie – Felix King - Felicity's younger brother and one of Anne's best friends, he is a nice and inventive boy. He owns. Linda SorensenHetty King - The Avonlea schoolteacher. Like Marilla, she has faith in her students. Patricia Gage – Marilla Cuthbert - Anne's adoptive mother, she has a strict, no-nonsense attitude but loves Anne much. She is the second most predominant character in the series, after Anne. Anne Anglin – Peg Bowen - an eccentric woman of whom the kids are afraid until they learn she holds the answers to many of their problems, she appears in "The Stray", "Taffy", "One True Friend", "Lost And Found", "The Ice Cream Promise", "The Witch of Avonlea", "A Square Peg", "A Condition of Superstition".

Tracey MooreDryad - a wood nymph of Anne's imagination who helps Anne in solving problems. Patricia Hamilton – Rachel Lynde - Marilla's friend and the most gossipy woman in Avonlea, she appears in "Babysitter Blues", "Idle Chatter", "The Ice Cream Promise", "The Avonlea Herald", "A Condition Of Superstition", "A Better Mousetrap". Unknown – Caesar - Felix's dog, rowdy and out of control, he likes to escape by biting away the rope. He only appears in two episodes, "A Condition Of Superstition", "No Anne Is An Island", he is a fox terrier. Keith Dinicol and Keith KnightThe Willows - Two weeping willow trees that Anne talks to in her imagination, they seem to have different personalities, one is dramatic and stuffy, the other is grumpy and cynical. They appear in the episodes "The Stray", "Taffy", "One True Friend", "The Witch of Avonlea", "A Condition Of Superstition". Richard Binsley – Mr. Lawson Adrian Truss – Mr. Gresham Andrew Craig – Perry No Voice – The Swings - The local swing set, they have supernatural powers to tell where lost people are.

They only appear in "A Condition Of Superstition" because Anne and her friends asked so many questions that their powers seemed to wear off. In 2002, an animated Anne of Green Gables movie was titled Anne: Journey to Green Gables; this 85-minute direct-to-video film was a prequel to the live action Anne of Green Gables series. The cast voices included Lally Cadeau, Cedric Smith, Kathryn Greenwood, Patricia Hamilton, all of whom had appeared in previous Sullivan Entertainment productions. September 20, 2002 March 15, 2002 Official website Anne of Green Gables: The Animated Series on IMDb Anne of Green Gables: The Animated Series at epguides.com

Athol Murray College of Notre Dame

Athol Murray College of Notre Dame is a private, independent, co-educational boarding high school rooted in the Catholic tradition and open to students of all faith backgrounds. Athol Murray College of Notre Dame is committed to developing young men and women to become purposeful leaders with virtuous character. Athol Murray College of Notre Dame is located in Wilcox, Canada, it was founded by the Sisters of Charity of St. Louis in 1920 as St. Augustine school when they established Notre Dame of the Prairies Convent; the school was renamed to honour the contributions of Father Athol Murray. A noted, stained glass window honours 67 of the college's alumni who died in World War II. In 1920, the Sisters of Charity of St. Louis opened the Notre Dame of the Prairies Convent and St. Augustine's residential elementary and high school for boys and girls at Wilcox, Saskatchewan. Father Athol Murray was appointed to St. Augustine's parish in Wilcox, Saskatchewan, in 1927; the institution's name was changed to honour his contributions.

In the beginning, the College had central heating. In 1930, fees were $18 per month. Père Murray accepted students on the basis that they desired an education, not on their ability to pay. A side of beef, a chicken, a bucket of coal and produce were accepted instead of money. Students came from everywhere and from every type of social and religious background. Murray was assisted by Sister Mary Edith McCullough, her teaching career spanned 30 years at Wilcox. Sr. Edith ran the elementary and high schools while Père spent most of his time with the students in the Arts programs. In 1933, Père Murray succeeded in obtaining an official affiliation with the University of Ottawa. Père Murray believed in the Greek philosophy of developing the mind and spirit and envisioned a school that could develop great scholars and athletes through equal emphasis on the disciplines of academics and faith. Notre Dame's longstanding success in developing well-balanced individuals is a testament to that vision. Though Murray died in 1975, his legacy lives on.

Père's beloved Notre Dame College continues to produce many of North America's finest student athletes through a balanced program that emphasizes the values of good character and community living. Père's motto "Luctor et Emergo" is still reinforced today; the Institute for Stained Glass in Canada has documented the stained glass at Athol Murray College of Notre Dame. Dedicated to 67 ex-students of Notre Dame College who served and died during World War II. In addition to its academic programs, the College has many sports teams; the most notable are the Saskatchewan Junior Hockey League's Notre Dame Hounds. There are a number of minor hockey teams playing under the SHA banner, as well as members of the Canadian Sport School Hockey League. Notre Dame fields three midget'AAA' teams: two male teams, one female team; the midget'AAA' program has won a total of five national championships: four on the male side and one on the female side. Former Tampa Bay Lightning forwards Vincent Lecavalier and Brad Richards played together in the school's AAA Bantam program, while numerous others have gone on to be drafted into the NHL.

Notre Dame runs high school athletics programs in basketball, football, volleyball, softball and field and wrestling. The Hounds of Notre Dame have had a choir for many years, they sing a "Prayer And Victory March" after every athletic competition. This song is derived from early Hounds and contains the part of the University of Notre Dame's fight song, due to the contributions toward Père's Tower of God by a Notre Dame alumni. "Dear Notre Dame. Thy loyal sons, Thy banners proudly bear. We pledge to Our love and our devotion, We beg thee hear and grant our prayers. Oh guide our steps. What though the odds be great or small, Old Notre Dame will win over all, While her loyal sons are marching, Onward to victory, cheer for old Notre Dame, Wake up the echoes cheering her name, Send a volley, cheer on high, Shake down the thunder from the sky! What though the odds be great or small, Old Notre Dame will win over all, While her loyal sons are marching Onward to victory, Notre Dame!" Père Murray and the Hounds, the story of Saskatchewan's Notre Dame College, by Jack Gorman, ISBN 0921835043 Père - A Père Murray Compendium, compiled by Jack Gorman ISBN 0921835108 Legacy... the treasures of Notre Dame, by Jack Gorman The Hounds of Notre Dame - a movie based on the compelling story of Père Murray and the Hounds Tales from the Shacks: Pere Murray's Notre Dame College, by Richard Dukes ISBN 0921835248 Notre Dame of the Prairies, by Alice Henderson ISBN 0919829082 The Rink: Stories from Hockey's Home Towns, by Chris Cuthbert and Scott Russell ISBN 0670875503 Official website TABS Association of Boarding Schools Athol Murray College of Notre Dame Profile