Paronychia is a nail infection, an tender bacterial or fungal infection of the hand or foot, where the nail and skin meet at the side or the base of a finger or toenail. The infection can start or gradually. Paronychia is misapplied as a synonym for whitlow or felon; the term is from Greek: παρωνυχία from para, "around", onyx, "nail" and the abstract noun suffix -ia. The skin presents as red and hot, along with intense pain. Pus is present, along with gradual thickening and browning discoloration of the nail plate. Acute paronychia is caused by bacteria. Paronychia is treated with antibiotics, either topical or oral or both. Chronic paronychia is most caused by a yeast infection of the soft tissues around the nail but can be traced to a bacterial infection. If the infection is continuous, the cause is fungal and needs antifungal cream or paint to be treated. Risk factors include washing hands and trauma to the cuticle such as may occur from repeated nail biting. In the context of bartending, it is known as bar rot.
Prosector's paronychia is a primary inoculation of tuberculosis of the skin and nails, named after its association with prosectors, who prepare specimens for dissection. Paronychia around the entire nail is sometimes referred to as runaround paronychia. Painful paronychia in association with a scaly, keratotic rash of the ears, nose and toes may be indicative of acrokeratosis paraneoplastica, associated with squamous cell carcinoma of the larynx. Paronychia can occur with diabetes, drug-induced immunosuppression, or systemic diseases such as pemphigus. Paronychia may be divided as follows: Acute paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less a toe, lasting less than six weeks; the infection starts in the paronychium at the side of the nail, with local redness and pain. Acute paronychia is caused by direct or indirect trauma to the cuticle or nail fold, may be from minor events, such as dishwashing, an injury from a splinter or thorn, nail biting, biting or picking at a hangnail, finger sucking, an ingrown nail, or manicure procedures.
Chronic paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less a toe, lasting more than six weeks. It is a nail disease prevalent in individuals whose hands or feet are subject to moist local environments, is due to contact dermatitis. In chronic paronychia, the cuticle separates from the nail plate, leaving the region between the proximal nail fold and the nail plate vulnerable to infection, it can be the result of dish washing, finger sucking, aggressively trimming the cuticles, or frequent contact with chemicals. Alternatively, paronychia may be divided as follows: Candidal paronychia is an inflammation of the nail fold produced by Candida albicans. Pyogenic paronychia is an inflammation of the folds of skin surrounding the nail caused by bacteria. Acute paronychia is a pyogenic paronychia as it is caused by a bacterial infection; when no pus is present, warm soaks for acute paronychia are reasonable though there is a lack of evidence to support its use.
A simple treatment with over-the-counter topical antibiotics such as mupirocin, bacitracin/neomycin/polymyxin B may suffice for mild cases. Antibiotics such as clindamycin or cephalexin are often used, the first being more effective in areas where MRSA is common. If there are signs of an abscess drainage is recommended. Chronic paronychia is treated by avoiding whatever is causing it, a topical antifungal, a topical steroid. In those who do not improve following these measures, oral antifungals and steroids may be used or the nail fold may be removed surgically. "Paronychia Nail Infection". Dermatologic Disease Database. American Osteopathic College of Dermatology. Retrieved 2006-07-12
VReel was a video sharing web site that allowed users to upload and view high resolution videos by use of a proprietary video codec. The site was in open beta in an effort to replace the now defunct Stage6 site with a viable alternative. Using a similar style to Stage6, VReel received a licence from DivX, Inc. to use their video codec, signed an agreement with Edgecast to distribute the web site globally. VReel began in 2008 under the title DivXIt.net, drawing attention from the Internet community by means of social bookmarking web sites, such as Digg. DivXIt.net's inbound traffic gained the attention of DivX, Inc. who issued a cease and desist order against the web site for trademark infringement. Following this event, DivXIt staff responded to the order offering to sign the domain name over to DivX, Inc. in return for a free licence for the web site. This arrangement was met and the site renamed itself VReel, the DivXIt.net domain was transferred to DivX, Inc. Having moved to a new domain, a short time VReel was contacted by Limelight Networks, was offered a hosting plan on their network.
The original beta test of VReel.net was scheduled to begin on 18 May 2008, with the full release occurring at the 31st of the same month. However, on May 23, VReel released a statement stating that its programming team was late in releasing the beta version of the site, that as of that date, their contract allowed for 2 more days to deliver the beta release; this did not occur however, the site's lead developer started an arbitration process. The May 23rd statement stated that a new development team was to be selected "in the next 5 days", a period which would end on May 27. VReel servers went down on Saturday 31 May 2008 due to a fire at The Planet data center; the site recovered on Wednesday 4 June 2008. On August 3, 2008, VReel disabled all video playback; this was due to multiple "leech sites" stealing bandwidth and causing high operating costs that were needed to fund the development and launch of the second beta. VReel announced that the web site would be back online by August 30, 2008. Financial problems forced the company to postpone.
In October 2008, VReel announced a partnership with Lavasoft. Eoghan stated "VReel.net, the home of high definition and high speed online video has today announced its software partnership with Lavasoft, for their acclaimed and award winning Ad-Aware anti-spyware software. VReel Beta 2 introduced several new features, including expanded community features and premium accounts. On November 10th, VReel enabled private access to its second beta, they introduced beta testers in waves, applications were available for users to apply. The second wave began on November 14, the third Began on the 21st. During the closed beta period there were free keys given to those who won "Treasure Hunts" that Eoin made. VReel announced a 24-hour trial period during which the site would be accessible to the public. Following the 24-hour trial on 28 November, the site remained open indefinitely. VReel acquired the StageHD.com domain, forwarded all traffic to the VReel video portal. VReel's traffic share continued to rise since its launch.
The site continued to rise. In July 2009, the site was ranked #30,500 by Alexa. By October 2009, the site had risen to rank #16,824. May 5, 2009 the site announced that in addition to its original partnership with EdgeCast Networks, it is now directly peering with various ISPs, including Level-3 and AT&T; the announcement stated the site's backend was moved to a new set of servers. It was hosted on 3 servers in Germany and moved to 10 servers in the United States. VReel has been working on their own webplayer, based on the VLC media player, to replace the DivX Web Player. With the new web player, VReel would natively support 4 formats; the VReel Player has not yet been released to the public. The May 2009 announcement stated that contrary to previous announcements, the VReel Player will not be based on the VLC player and neither will it be open source. After the project has been put on hold it has now been continued and will be built from the ground up in closed source. Among concerns, the primary concern for going closed-source was the confrontation with too many security issues when having the source open for everyone.
The VReel Player would be redeveloped under a closed source license, will be capable of DivX, XviD and h.264 playback. As of January 24th 2010, We have decided to take the decision to close VReel as a user-generated HD DivX Video portal. VReel was created as a replacement for DivX's popular Stage6 platform - but due to its popularity, became impossible to financially sustain in a time of increasing development costs, plummeting advertisement and revenue sources. Following a mass hardware failure at our main server farm, we have decided not to relaunch VReel in its current environment. VReel is being redeveloped as a HD Video search engine, with several great features not yet seen in the search engine marketplace. We hope to have this launched within April 2010. Our forums will remain open for discussion, where we'll be unveiling a string of new projects from VReel's founding team. We'd like to thank everyone who contributed to VReel over the past two years - it's been an amazing experience. Official website
El Sonido Nuevo, subtitled/translated The New Soul Sound, is an album by Latin jazz vibraphonist Cal Tjader and pianist Eddie Palmieri recorded in 1966 and released on the Verve label. The Allmusic review by Scott Yanow stated, "El Sonido Nuevo is a popular collaboration between vibraphonist Cal Tjader and pianist Eddie Palmieri. Despite the claims of greatness expressed in the liners, much of the music is quite lightweight although enjoyable enough, the easy listening melodies and accessible rhythms hold one's interest". All compositions by Cal Tjader and Eddie Palmieri except where noted "Los Jibaros" - 2:40 "Gaujira en Azul" - 3:20 "Ritmo Uni" - 3:45 "Picadillo" - 7:00 "Modesty" - 2:30 "Unidos" - 4:35 "On a Clear Day" - 1:50 "El Sonido Nuevo" - 5:50Recorded at Van Gelder Studio in Englewood Cliffs, NJ on May 24, 1966, May 25, 1966 and May 26, 1966, Cal Tjader - vibraphone Eddie Palmieri - piano, arranger Julian Priester, Jose Rodriguez, Mark Weinstein - trombone Barry Rogers - trombone, congas George Castro - flute, percussion Bobby Rodriguez- bass Tommy Lopez, Manny Oquendo - drums Ismael Quintana - percussion
George was a snail of the species Achatinella apexfulva, the last known individual of his species. Achatinella apexfulva was endemic to forests of Hawaii, its populations declined due to predation by the rosy wolfsnail, introduced to Hawaii in the 1950s to control agricultural pests. The species was listed as federally endangered in 1981. In 1997, all known remaining specimens of A. apexfulva were bred in captivity. Most offspring died of unknown causes; this individual, born in a laboratory at the University of Hawaii at Manoa, was named George, after Lonesome George, a Pinta Island tortoise, the last of its kind. George's parents were collected from the last known wild population of A. apexfulva, in a few trees near Oahu's Poamoho trail. At the time of his birth, about 20 A. apexfulva individuals survived in captivity. George has been described as "a thumbnail-size whorl of dark brown and tan." Although referred to using the pronoun "he", George was a hermaphrodite. He could not reproduce without a mate.
While George was alive, it became a tradition for snail researchers to stop at the spot where the last A. apexfulva were found and scan the trees with binoculars, in the hope of finding him a mate. As of 2016, George lived in a terrarium at the University of Hawaii. At the time of his death, George was kept in a trailer on the outskirts of Kailua, cared for by researcher David Sischo, director of the state's Snail Extinction Prevention Program, colleagues. In August 2018, George was among 2000 snails temporarily transferred from Kawainui Marsh to the main Department of Land and Natural Resources offices in downtown Honolulu, to protect against damage from Hurricane Lane. On January 1, 2019, George died at age 14, leaving the species extinct, his body was discovered the following morning. As of 2019, George's remains are stored in a cupboard labelled "DEATH CABINET", alongside the bodies of other dead snail specimens. In 2017, researchers collected a two-millimetre sample of George's foot, now kept in storage at San Diego's Frozen Zoo, to be available for possible future cloning attempts
Free Form Patterns, is an album by blues musician Lightnin' Hopkins backed by the rhythm section of The 13th Floor Elevators recorded in Texas in 1968 and released on the International Artists label. AllMusic's Al Campbell stated: "While not as revolutionary as John Lee Hooker's sessions with Canned Heat, Free Form Patterns steers clear of the late-'60s psychedelic trappings that screwed up such similar sessions as Electric Mud. No one tried to bend Hopkins to fit a foreign musical approach on Free Form Patterns. Record Collector observed "Free Form Patterns isn’t some hippy hybrid, it’s a pure blues album – scrub that. Raul de Gama said "True to form – to free form – Lightnin’ Hopkins’ music unfolds as the avant-garde of the day, his notes carry a singular drawl – a Texas drawl – as they roll over each other to form that seminal wave travelling so fast, yet as sinuous as it makes its way into the inner ear of the mind... The considerable degree of balance and integration of melody and rhythm, of composition and tradition is impressively maintained throughout".
The Penguin Guide to Blues Recordings said: "Despite these interpolations it's a rather lacklustre affair". All compositions by Sam "Lightnin'" Hopkins except where noted "Mr. Charlie" – 7:02 "Give Me Time to Think" – 3:49 "Fox Chase" – 2:53 "Mr. Ditta's Grocery Store" – 5:30 "Open Up Your Door" – 3:54 "Baby Child" – 3:35 "Cooking's Done" – 3:48 "Got Her Letter This Morning" – 4:57 "Rain Falling" – 4:33 "Mini Skirt" – 3:10 Lightnin' Hopkins – electric guitar, vocals Duke Davis – bass Danny Thomas – drumsBilly Bizor and vocals Lelan Rogers – producer Jim Duff – engineer