Port Morris is a mixed use, primarily industrial neighborhood geographically located in the southwest Bronx, New York City. The neighborhood is part of Bronx Community Board 1. Its boundaries are the Major Deegan Expressway and Bruckner Expressway to the north, East 149th Street to the east, the East River to the southeast, the Bronx Kill to the south, and the Harlem River to the west. Its ZIP Codes are 10451 and 10454. The neighborhood is served by the NYPD's 40th Precinct.

The Bruckner Expressway is a freeway in the borough of the Bronx in New York City. It carries Interstate 278 (I-278) and I-95 from the Triborough Bridge to the south end of the New England Thruway at the Pelham Parkway interchange. The highway follows a mostly northeast–southwest alignment through the southern portion of the borough, loosely paralleling the course of the East River. It connects to several major freeways including the Bronx River Parkway, and at the Bruckner Interchange, it connects to the Cross Bronx Expressway, the Hutchinson River Expressway, and the Hutchinson River Parkway.