Prostaglandin G2

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Prostaglandin G2
Prostaglandin G2.svg
Names
IUPAC name
(5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S)-3-Hydroperoxy-1-octen-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl}-5-heptenoic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
EC Number 200-662-2
KEGG
Properties
C20H32O6
Molar mass 368.464
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references


Prostaglandin G2 is an organic peroxide belonging to the family of prostaglandins.[1] The compound has been isolated as a solid, although it is usually used in vivo, it quickly converts into prostaglandin H2, a process catalyzed by the enzyme COX.

Prostaglandin G2 is produced from the fatty acid arachidonic acid, the reaction, an oxygenation, requires the enzyme cyclooxygenase, which inserts two molecules of O2 into the C-H bonds of the substrate acid.[1][2]

References[edit]

  1. ^ a b van der Donk, Wilfred A.; Tsai Ah-Lim; Kulmacz Richard J. (2002). "The cyclooxygenase reaction mechanism". Biochemistry. 41: 15451–8. doi:10.1021/bi026938h. 
  2. ^ "Prostaglandin G2". Santa cruz biotechnology, inc. Retrieved 27 April 2015.