Puthuppally is one of the few major centers and towns in the Kottayam district of Kerala, India as many areas can be reached only via Puthuppally. The community is known for its ancient Malankara Orthodox Syrian Church, Puthuppally Palli. The town is growing further owing to the increasing number of major roads connecting it to other major towns in the region.

St.George Orthodox Church Puthuppally is a prominent church that belongs to the Malankara Orthodox Syrian Church. This church is situated beside the Puthuppally - Changanassery road about a kilometre from the Puthuppally junction, on the eastern bank of the Kodoor river. The surrounding areas of church are panoramic and very beautiful. The old church was well preserved church with wall murals dating back to ancient times. These unique wall murals have been painted using vegetable dyes. Former Chief Minister of Kerala Oommen Chandy is buried in this church.