Pyrenees Highway is a rural highway in western Victoria, Australia, linking Glenelg Highway in Glenthompson to Calder Highway in Elphinstone. It intersects with the region's major road freight route, Western Highway in Ararat, in addition to Midland Highway in Castlemaine and Sunraysia Highway in Avoca. It was named after the Pyrenees ranges the highway runs through. This name covers many consecutive roads which are not widely known to most drivers except for the easternmost section, as the entire allocation is best known by the name of its last constituent part: Maroona–Glenthompson Road, Mortlake–Ararat Road and Pyrenees Highway proper. This article will deal with the entire length of the corridor for sake of completion, as well to avoid confusion between declarations.

Calder Highway is a rural highway in Australia, linking Mildura and the Victoria/New South Wales border to Bendigo, in North Central Victoria. South of Bendigo, where the former highway has been upgraded to freeway-standard, Calder Freeway links to Melbourne, subsuming former alignments of Calder Highway; the Victorian Government completed the conversion to freeway standard from Melbourne to Bendigo on 20 April 2009.