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Q fever

Q fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects humans and other animals. This organism is uncommon, but may be found in cattle, sheep and other domestic mammals, including cats and dogs; the infection results from inhalation of a spore-like small-cell variant, from contact with the milk, feces, vaginal mucus, or semen of infected animals. The disease is tick-borne; the incubation period is 9–40 days. Humans are vulnerable to Q fever, infection can result from a few organisms; the bacterium is an obligate intracellular pathogenic parasite. Incubation period is two to three weeks; the most common manifestation is flu-like symptoms with abrupt onset of fever, profuse perspiration, severe headache, muscle pain, joint pain, loss of appetite, upper respiratory problems, dry cough, pleuritic pain, chills and gastrointestinal symptoms, such as nausea and diarrhea. About half of infected individuals exhibit no symptoms. During its course, the disease can progress to an atypical pneumonia, which can result in a life-threatening acute respiratory distress syndrome, whereby such symptoms occur during the first four to five days of infection.

Less Q fever causes hepatitis, which may be asymptomatic or becomes symptomatic with malaise, liver enlargement, pain in the right upper quadrant of the abdomen. Whereas transaminase values are elevated, jaundice is uncommon. Retinal vasculitis is a rare manifestation of Q fever; the chronic form of Q fever is identical to inflammation of the inner lining of the heart, which can occur months or decades following the infection. It is fatal if untreated. However, with appropriate treatment, the mortality falls to around 10%. Diagnosis is based on serology rather than looking for the organism itself. Serology allows the detection of chronic infection by the appearance of high levels of the antibody against the virulent form of the bacterium. Molecular detection of bacterial DNA is used. Culture is technically difficult and not available in most microbiology laboratories. Q fever can cause endocarditis. Q fever hepatitis manifests as an elevation of alanine transaminase and aspartate transaminase, but a definitive diagnosis is only possible on liver biopsy, which shows the characteristic fibrin ring granulomas.

Protection is offered by Q-Vax, a whole-cell, inactivated vaccine developed by an Australian vaccine manufacturing company, CSL Limited. The intradermal vaccination is composed of killed C. burnetii organisms. Skin and blood tests should be done before vaccination to identify pre-existing immunity, because vaccinating people who have an immunity can result in a severe local reaction. After a single dose of vaccine, protective immunity lasts for many years. Revaccination is not required. Annual screening is recommended. In 2001, Australia introduced a national Q fever vaccination program for people working in “at risk” occupations. Vaccinated or exposed people may have their status recorded on the Australian Q Fever Register, which may be a condition of employment in the meat processing industry. An earlier killed vaccine had been developed in the Soviet Union, but its side effects prevented its licensing abroad. Preliminary results suggest. Published trials proved that use of a registered phase vaccine on infected farms is a tool of major interest to manage or prevent early or late abortion, repeat breeding, silent oestrus and decreases in milk yield when C. burnetii is the major cause of these problems.

Treatment of acute Q fever with antibiotics is effective and should be given in consultation with an infectious diseases specialist. Used antibiotics include doxycycline, chloramphenicol, ciprofloxacin and hydroxychloroquine. Chronic Q fever is more difficult to treat and can require up to four years of treatment with doxycycline and quinolones or doxycycline with hydroxychloroquine. Q fever in pregnancy is difficult to treat because doxycycline and ciprofloxacin are contraindicated in pregnancy; the preferred treatment is five weeks of co-trimoxazole. The pathogenic agent is found worldwide, with the exception of New Zealand; the bacterium is sustainable and virulent: a single organism is able to cause an infection. The common source of infection is inhalation of contaminated dust, contact with contaminated milk, meat, or wool, birthing products. Ticks can transfer the pathogenic agent to other animals. Transfer between humans seems rare and has so far been described in few cases; some studies have shown more men to be affected than women, which may be attributed to different employment rates in typical professions.

“At risk” occupations include: Veterinary personnel Stockyard workers Farmers Sheep shearers Animal transporters Laboratory workers handling infected veterinary samples or visiting abattoirs People who cull and process kangaroos Hide workers Q fever was first described in 1935 by Edward Holbrook Derrick in slaughterhouse workers in Brisbane, Queensland. The "Q" was applied at a time when the causative agent was unknown; the pathogen of Q fever was discovered in 1937, when Frank Macfarlane Burnet and Mavis Freeman isolated the bacterium from one of Derrick's pat

The New Exhibit

"The New Exhibit" is an episode of the American television anthology series The Twilight Zone. In this episode a museum worker takes a set of wax figures into his home, where they begin to show the homicidal tendencies of the famous murderers they depict. Martin Senescu works at a wax museum, his boss and best friend, Mr. Ferguson, informs him that, due to a long-term decline in sales and his desire to retire, he is selling the museum, which will be torn down and replaced by a supermarket; the dispirited Martin, desperate to save the figures from the "Murderer's Row" exhibit, volunteers to keep them at his house until a buyer can be found for them. Martin's wife, becomes frustrated at having the figures in their basement, they require an air conditioner to keep from melting, due to the hot weather the resultant electric bill wipes out their savings in just a month. Martin makes only perfunctory efforts at finding a buyer for the figures, instead spending most of his time tending to them. Emma is disconcerted by this when he begins talking about them and to them as if they were alive.

Her brother, advises her to shut off the air conditioning so that the figures melt. After one last effort to convince Martin to return the figures to Ferguson's care, Emma sneaks out of bed one night and goes down to the basement; when she tries to shut off the air conditioner, the wax figure of Jack the Ripper stabs her. The next morning, Martin discovers Jack's bloody knife. Realizing no one will believe Emma was killed by a wax figure, he buries her under the basement floor; the next day, Dave pays a visit. Martin nervously claims to have gotten rid of the wax figures, which arouses Dave's suspicions when he hears the air conditioner hum and finds the basement door locked; when he presses Martin further about Emma's whereabouts, Martin rushes him out of the house. Dave sneaks into the basement through the back entrance. While he is examining the area, the wax figure of Hicks strikes Dave with its axe. Martin comes down to find the carnage. Several weeks Ferguson comes by to tell Martin that he has sold the figures to the legendary Marchand's Wax Museum in Brussels.

Martin is still reluctant to give up the wax figures he's so cared for. While he goes upstairs and makes tea, Ferguson takes measurements of the figures for the buyer; when he makes a passing remark about Landru's width, Landru lowers the rope around his neck and strangles him. Martin finds Ferguson's body. Deeming this the last straw, Martin rebukes the grabs a crowbar, planning to smash them; the wax figures advance on Martin. They tell him that he was the one that murdered Emma and Ferguson as Martin points out that he wasn't in the basement when any of the murders were committed. Martin screams. Years at Marchand's, the five figures of the murderers are now accompanied by a wax figure of Martin, believed to have killed Emma and Ferguson. DeVoe, Bill. Trivia from The Twilight Zone. Albany, GA: Bear Manor Media. ISBN 978-1-59393-136-0. Grams, Martin; the Twilight Zone: Unlocking the Door to a Television Classic. Churchville, MD: OTR Publishing. ISBN 978-0-9703310-9-0. "The New Exhibit" on IMDb "The New Exhibit" at TV.com

We are Spindye

We are Spindye is a Swedish fashion tech company that has developed a sustainable coloring method for synthetic textiles which reduces the environmental impact compared to the traditional dyeing process. The company was founded by Martin Berling in 2014. Headquartered in Stockholm, Sweden, We are Spindye has since it hit the market had colabs with brands such as Quiksilver, Peak Performance, Bergans of Norway, Roxy and Fjällräven. We are Spindye was founded by Martin Berling in 2014. While working in the American clothing industry, Berling realized that the process of dyeing textiles had a massive environmental impact. With the aim to reduce the ecological footprint of the clothing industry, Berling developed a way of coloring polyester fabrics using a process that requires less water and fewer chemicals than the traditional dyeing process. According to Berling, the principles of the process he developed had been used by the car industry for decades. In 2016 Swedish outdoor company Fjällräven became the first company to use the We are Spindye technology when they launched Re-Kånken, a remake of Fjällräven’s iconic children’s backpack Kånken first released in 1978.

Re-Kånken backpacks are made of recycled polyester sourced from 11 plastic water bottles. By January 2018 the number of colabs had grown to eight and included, besides Fjällräven, Bergans of Norway, Peak Performance, Pyua and Odd Molly. In the fall of 2018 We are Spindye announced that Swedish fashion brand Filippa K had chosen to use Spindye-colored fabrics in one of the garments of their Front Runners collection, a collection consisting of garments developed as sustainable as possible. At the end of August 2018 We are Spindye received a substantial cash boost when Dutch duo Textile innovation Fund and Social Impact Ventures along with Bestbase Group from China invested a combined total of 3 million euros in the company. According to Social Impact Ventures’ Eske Scavenius, who took a seat on the board of We are Spindye as a result of the investment, the capital injection would be used to increase marketing and production capacity. We are Spindye offer clothing companies a sustainable coloring method based on solution dyeing.

Traditional dyeing means first producing the fiber and dipping the fiber in dye to add the color. This requires a lot of hot liquid chemicals. Solution dyeing means adding the color pigment earlier in the manufacturing process, when the polyester is just little pellets. Once these pellets are colored, they are melted and turned into fibres, which are spun into yarn. According to We are Spindye their method of coloring reduces water usage by 75%, chemical usage by 90%, energy consumption by 25% and CO2 emissions by 30% compared to traditional dyeing; the claims have been validated by Swedish NGO Swerea. The We are Spindye color catalog consists of nearly 2000 colors, all of which have its own recipe, co-produced with NCS, to ensure that the color will always be the same regardless of the fabric or the factory. We are Spindye. In April 2018 the company was awarded Eco Brand of the year in Sportfack Gear Of The Year and in June 2018 We are Spindye won the apparel category of the Scandinavian Outdoor Award hosted by Scandinavian Outdoor Group.

In August 2018 We Are Spindye won the fashion tech category of Encouragement for Action 2018 award established by Stockholm Fashion District. Bergans of Norway Fjällräven Makia Odd Molly Peak Performance Pyua Quiksilver Roxy

La Salle Explorers men's basketball

The La Salle Explorers men's basketball program represents La Salle University in college basketball. The Explorers, a member of the Big 5, have long-standing rivalries with multiple institutions including Temple University, University of Pennsylvania, Saint Joseph's University, Villanova University. Another major rival is Drexel University, a member of the City 6; the program has been rated the 53rd "Greatest College Basketball Program of All-Time" by Street & Smith's magazine and 71st by the ESPN College Basketball Encyclopedia. La Salle has won one National Championship, one National Invitation Tournament Championship, advanced to two Final Fours; the Explorers have made 12 NCAA Tournament appearances, won eight Philadelphia Big 5 city championships, four Metro Atlantic Athletic Conference Championships. The program is one of only two schools to have two players in the top 25 in all-time NCAA scoring – Lionel Simmons and Michael Brooks. It's had three National Players of the Year; the Explorers have appeared in the NCAA Tournament 12 times.

Their combined record is 14–11. They were National Champions in 1954; the Explorers have appeared in the National Invitation Tournament 12 times. Their combined record is 9–11, they were NIT champions in 1952. La Salle has an extensive history of players who played professional basketball, including: Michael Brooks, 1980 College Player of the Year Joe Bryant, father of former pro Kobe Bryant Rasual Butler Larry Cannon Ken Durrett Bobby Fields Larry Foust, eight-time NBA All-Star selection Tom Gola, NBA Hall of Famer, 1955 College Player of the Year B. J. Johnson Tim Legler, current basketball analyst for ESPN, 4th all-time in NBA three-point shooting percentage Ralph Lewis Doug Overton Jim Phelan Lionel Simmons, 1990 College Player of the Year Steven Smith Fatty Taylor Randy Woods Bernie Williams Previous head coach Dr. John Giannini coached at Rowan College, where he won the NCAA Division III national championship in 1996, the University of Maine, where he left with the Black Bears' best winning percentage in school history.

On April 8, 2018, La Salle announced Ashley Howard as the next head coach of the Explorers. Howard served as an assistant coach under Jay Wright at Villanova University; as assistant coach, he helped lead the Wildcats to two NCAA Division 1 basketball championships. Official website

Associate international cricket in 2019–20

The 2019–20 Associate international cricket season is from September 2019 to April 2020. All official twenty over matches between Associate members of the ICC will have full Twenty20 International or Women's Twenty20 International status, as the International Cricket Council granted T20I status to matches between all of its members from 1 July 2018 and 1 January 2019; the season includes all T20I/WT20I cricket series involving ICC Associate members, that are of lesser notability than series covered in International cricket in 2019–20. More than 75% of men's T20I matches in the 2019 calendar year featured Associate teams; the coronavirus pandemic impacted on several international cricket tournaments. The first Associate international matches postponed included the ACA Africa T20 Cup Finals, due to be held in Kenya, the 2020 Malaysia Cricket World Cup Challenge League A and the 2020 United States Tri-Nation Series. Top 2 advanced to the gold medal match Bottom 2 advanced to the bronze medal match advanced to the gold medal match advanced to the bronze medal match Advance to Asia Cup Qualifier The tournament was postponed in March 2020 due to the coronavirus pandemic.

International cricket in 2019–20 Impact of the 2019–20 coronavirus pandemic on sports#Cricket

Stranglers in the Night

Stranglers in the Night is the eleventh studio album by The Stranglers and the first release on the band's own record label, Psycho, in 1992. It opened the recording career of the Stranglers MK II, with Paul Roberts on vocals and John Ellis on guitar; the band returned to less "produced" sound. Styles vary from ballads such as "Southern Mountains" and "Grand Canyon" to the fast-paced "Sugar Bullets" and "Brainbox"; the North American version of this album contained three extra tracks, which were B-sides in the UK. The album peaked at No. 33 in the UK Albums Chart in September 1992. The single "Heaven And Hell" was released from the album, peaked at No. 46 in the UK Singles Chart in August 1992. The follow-up single, "Sugar Bullets", failed to chart. All tracks written by The Stranglers; the StranglersPaul Roberts – vocals Jean-Jacques Burnelbass, vocals John Ellis – guitar, vocals Dave Greenfieldkeyboards, vocals Jet Blackdrums, percussionAdditional musiciansSimon Morton – additional percussionTechnicalMike Kemp – production Richard Norris – engineering Jill Furmanovsky – photography Cactus – sleeve design Simon J. Webb – Psycho Records logo design