Quinagolide

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Quinagolide
Struktur von Quinagolid
Structure without stereochemistry
Clinical data
Trade names Norprolac
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
Formula C20H33N3O3S
Molar mass 395.56 g/mol
 NYesY (what is this?)  (verify)

Quinagolide (INN, BAN; brand name Norprolac) is a selective D2 receptor agonist that is used to reduce elevated levels of prolactin (hyperprolactinemia).[1] It has also been found to be effective in the treatment of breast pain.[2]

Stereochemistry[edit]

Quinagolide is a racemate composed of the following two enantiomers:[3]

Enantiomeres of Quinagolide
(+)-Quinagolid Structural Formula V1.svg
CAS-Nummer: 140630-79-1
(-)-Quinagolid Structural Formula V1.svg
CAS-Nummer: 140630-80-4

See also[edit]

References[edit]

  1. ^ Antonella Di Sarno; Maria Luisa Landi; Paolo Marzullo; Carolina Di Somma; Rosario Pivonello; Gaetana Cerbone; Gaetano Lombardi; Annamaria Colao (July 2000). "The effect of quinagolide and cabergoline, two selective dopamine receptor type 2 agonists, in the treatment of prolactinomas". Clinical Endocrinology. 53 (1): 53–60. doi:10.1046/j.1365-2265.2000.01016.x. PMID 10931080. 
  2. ^ Alfonso M Pluchinotta (20 April 2015). The Outpatient Breast Clinic: Aiming at Best Practice. Springer. pp. 167–. ISBN 978-3-319-15907-2. 
  3. ^ Rote Liste Service GmbH (Hrsg.): Rote Liste 2017 - Arzneimittelverzeichnis für Deutschland (einschließlich EU-Zulassungen und bestimmter Medizinprodukte). Rote Liste Service GmbH, Frankfurt/Main, 2017, Aufl. 57, ISBN 978-3-946057-10-9, S. 214.