Raynaud syndrome known as Raynaud's phenomenon, is a medical condition in which spasm of arteries cause episodes of reduced blood flow. The fingers, less the toes, are involved; the nose, ears, or lips are affected. The episodes result in the affected part turning white and blue. Numbness or pain occurs; as blood flow returns, the area burns. The episodes last minutes, but can last several hours. Episodes are triggered by cold or emotional stress; the two main types are primary Raynaud's, when the cause is unknown, secondary Raynaud's, which occurs as a result of another condition. Secondary Raynaud's can occur due to a connective-tissue disorder, such as scleroderma or lupus, injuries to the hands, prolonged vibration, thyroid problems, certain medications, such as birth control pills. Diagnosis is based on the symptoms; the primary treatment is avoiding the cold. Other measures include the discontinuation of stimulants use. Medications for treatment of cases that do not improve include calcium channel blockers and iloprost.
Little evidence supports alternative medicine. Severe disease may be complicated by skin sores or gangrene. About 4% of people have the condition. Onset of the primary form is between ages 15 and 30 and occurs more in females; the secondary form affects older people. Both forms are more common in cold climates, it is named after the French physician Maurice Raynaud, who described the condition in 1862. The condition can cause pain within the affected extremities and sensations of cold and/or numbness; this can be distressing to those who are undiagnosed, sometimes it can be obstructive. If someone with Raynaud's is placed into a cold climate, it could become dangerous; when exposed to cold temperatures, the blood supply to the fingers or toes, in some cases the nose or earlobes, is markedly reduced. These events are episodic, when the episode subsides or the area is warmed, the blood flow returns, the skin color first turns red, back to normal accompanied by swelling, a painful "pins and needles" sensation.
All three color changes are observed in classic Raynaud's. However, not all patients see all of the aforementioned color changes in all episodes in milder cases of the condition. Symptoms are thought to be due to reactive hyperemias of the areas deprived of blood flow. In pregnancy, this sign disappears owing to increased surface blood flow. Raynaud's has occurred in breastfeeding mothers, causing nipples to turn white and become painful. Raynaud's disease, or primary Raynaud's, is diagnosed if the symptoms are idiopathic, that is, if they occur by themselves and not in association with other diseases; some refer to primary Raynaud's disease as "being allergic to coldness". It develops in young women in their teens and early adulthood. Primary Raynaud's is thought to be at least hereditary, although specific genes have not yet been identified. Smoking increases frequency and intensity of attacks, a hormonal component exists. Caffeine and nonselective beta-blockers are listed as aggravating factors, but evidence that they should be avoided is not solid.
People with the condition are more to have migraines and angina. Raynaud's phenomenon, or secondary Raynaud's, occurs secondary to a wide variety of other conditions. Secondary Raynaud's has a number of associations: Connective tissue disorders: scleroderma Systemic lupus erythematosus Rheumatoid arthritis Sjögren's syndrome Dermatomyositis Polymyositis Mixed connective tissue disease Cold agglutinin disease Ehlers-Danlos syndrome Eating disorders: Anorexia nervosa Obstructive disorders: Atherosclerosis Buerger's disease Takayasu's arteritis Subclavian aneurysms Thoracic outlet syndrome Drugs: Beta-blockers Cytotoxic drugs – chemotherapeutics and most bleomycin Cyclosporin Bromocriptine Ergotamine Sulfasalazine Anthrax vaccines whose primary ingredient is the Anthrax Protective Antigen Stimulant medications, such as those used to treat ADHD OTC pseudoephedrine medications Occupation: Jobs involving vibration drilling and prolonged use of a string trimmer, suffer from vibration white finger Exposure to vinyl chloride, mercury Exposure to the cold Others: Physical trauma, such as that sustained in auto accidents or other traumatic events Lyme disease Hypothyroidism Cryoglobulinemia Cancer Chronic fatigue syndrome Reflex sympathetic dystrophy Carpal tunnel syndrome Magnesium deficiency Multiple sclerosis Erythromelalgia co-exists in patients with Raynaud's)Raynaud's can herald these diseases by periods of more than 20 years in some cases, making it the first presenting symptom.
This may be the case in the CREST syndrome. Patients with secondary Raynaud's can have symptoms related to their underlying diseases. Raynaud's phenomenon is the initial symptom that presents for 70% of patients with scleroderma, a skin and joint disease; when Raynaud's phenomenon is limited to one hand or one foot, it is referred to as unilateral Raynaud's. This is an uncommon form, it is always secondary to local or regional vascular disease, it progresses within several years to affect other limbs as the vascular disease progresses. Its pathophysiology includes hyperactivation of the sympathetic nervous system causing extreme vasoconstriction
Kamen Rider Zero-One is a Japanese tokusatsu drama. It is the first series of the Reiwa period; the cast of Kamen Rider Zero-One was announced on July 17, 2019. Hiden Intelligence is a tech company that develops HumaGears, a full fledged A. I.s in android bodies developed to be near indistinguishable from humans due to their lifelike appearance. Since MetsubouJinrai.net's cyber-terrorism became known, Hiden Intelligence began to use anti-viruses when they manufacture new HumaGears. After defeating MetsubouJinrai.net, Hiden Intelligence is still in danger from a far more dangerous threat than the cyber-terrorists. Aruto Hiden, born on May 1, 1997, is a 22-year-old kind-hearted failed comedian, appointed the CEO of Hiden Intelligence following the death of his grandfather, Korenosuke; as a child, he was taken care of by a HumaGear modeled after Soreo. After the HumaGear sacrificed himself to protect him during the Daybreak Incident, Aruto developed the ideal that HumaGears are the future for humanity, that they cannot turn evil on their own accord.
Thus, despite his initial disinterest in running Hiden Intelligence, he reconsiders. At first, Aruto wanted to maintain a secret identity as Zero-One. Due to A. I. M. S. Considering him an enemy however, he reveals himself to Isamu as a sign of trust and forms an uneasy alliance with him in order to learn more of MetsubouJinrai.net. Despite his goofy behavior, Aruto knows when to be serious and is smarter than he appears, such as when he revealed the cyber-terrorist group's existence during a press conference to prove Hiden Intelligence's innocence, he is aware of his own inexperience in running a company, being willing to listen to vice-president Fukuzoe's advice despite knowing the latter wants him out. During his first few battles, Aruto becomes troubled by how some of the Magias were HumaGears that had achieved technological singularity those he had formed a bond with, his belief that HumaGears can't turn evil is shattered by the revelation that MetsubouJinrai.net was formed and led by rogue HumaGears Horobi and Jin.
Despite this, Aruto was able to harden his resolve and continue fighting to protect people and HumaGears. After destroying MetsubouJinrai.net, Aruto finds himself targeted by ZAIA Enterprise's corrupt president Gai Amatsu, who seeks to destroy his reputation and take over Hiden Intelligence due to a grudge against his grandfather. During their "5-Part Workplace Competition", when Gai forced a HumaGear to turn into a Magia just so he could destroy them, Aruto snapped. Gai manipulates Aruto's rage to turn him into a berserker using the Metal Cluster Hopper Progrise Key to trap him within the Ark's control. Thanks to the HumaGears Aruto had bonded with however, he was cleansed of his anger and gained control over his new form so he could give Gai his first true defeat. Aruto becomes Zero-One by using the Hiden Zero-One Driver, the company's Rider system which only responds to the current CEO of Hiden Intelligence, with the SD card-like Progrise Keys, which contain animal data known as Rider Models that grant him access to a set of different armored forms each with their own unique abilities.
As Zero-One, he wields a multi-form Attache Weapon called the Attache Calibur, which can switch from its briefcase-like Attache Mode to the sword-like Blade Mode in order to perform one of two finishers: Kaban Strash or Kaban Dynamic. While the Attache Calibur is his primary weapon, he can use other Attache Weapons if necessary. By scanning the smartphone-like Hiden Risephone on the Hiden Zero-One Driver, Zero-One can summon his personal motorcycle, the Rise Hopper, from Hiden Intelligence's Zea satellite. Additionally, the Hiden Zero-One Driver grants Aruto the ability to directly interface with the Zea satellite's mainframe in unique ways; as Is explains, his brain seems to be able to process information at the same speed as most A. I. systems, as evidenced by him learning how to use the Driver just before his first battle. Rising Hopper: Zero-One's fluorescent yellow-colored default form, which grants enhanced jumping and kicking capabilities via the leg-mounted Rising Jumper, his finisher in this form is the Rising Impact.
As Zero-One's primary form, it can be combined with the armor of his auxiliary Progrise Keys: Biting Shark: Zero-One's teal-colored armor, which arms him with the Unlimited Chopper fin blades and grants underwater capabilities via the chest-mounted Labyrith Lung. His finisher in this armor is the Biting Impact. Flying Falcon: Zero-One's magenta-colored armor, which grants hovering capabilities via the shoulder-mounted Wing Fairlencers (ウイングフェアレンサ
Jonathan Scott Sieben, OAM is an Australian former butterfly swimmer of the 1980s, who won gold in the 200-metre butterfly at the 1984 Summer Olympics in Los Angeles Olympics. Hailing from Brisbane, Sieben was coached by Laurie Lawrence, made his debut at the young age of 15 at the 1982 Commonwealth Games in Brisbane, where he captured a bronze in the 200-metre butterfly, as well as gold in the medley relay. Sieben and Lawrence were given little chance. Sieben was known to his friends as The Shrimp, as he stood just 173 cm, in contrast to the dominant swimmer of the time, West Germany's Michael Gross, the world record holder, known as The Albatross with his 200 cm frame and 225 cm wingspan, he faced the 100-metre butterfly world record holder, the United States' Pablo Morales. Sieben swam in the wake of Gross and Morales in the first 150 metres, before storming home in the last 50 metres to claim the gold medal in a world record time of 1 m 57.04 s, more than four seconds faster than he had swum before.
He collected a bronze medal after swimming in the preliminaries of the medley relay. He was named the Young Australian of the Year in 1984. By the 1988 Summer Olympics in Seoul, Sieben's ability had waned, the selectors did not choose him for the 200 m butterfly, he finished fourth in the 100-metre butterfly. He continued onto the 1992 Summer Olympics in Barcelona, but failed to reach the final of the 100-metre butterfly individual event, he formed part of Australia's 4x100-metre medley relay team that finished 7th in the final, in a national record time of 3:42.65. Sieben was inducted into the Sport Australia Hall of Fame in 1985. List of Commonwealth Games medallists in swimming List of Olympic medalists in swimming World record progression 200 metres butterfly Andrews, Malcolm. Australia at the Olympic Games. Sydney, New South Wales: ABC Books. P. 397. ISBN 0-7333-0884-8. Howell, Max. Aussie Gold. Albion, Queensland: Brooks Waterloo. Pp. 257–261. ISBN 0-86440-680-0