"Run, Nigger, Run" is a folk song first documented in 1851. It is known from numerous versions. Responding to the rise of slave patrols in the slave-owning southern United States, the song is about an unnamed black man who attempts to run from a slave patrol and avoid capture. The song was released as a commercial recording several times, beginning in the 1920s, and it was included in the 2013 film 12 Years a Slave.

12 Years a Slave is a 2013 biographical drama film directed by Steve McQueen from a screenplay by John Ridley, based on the 1853 slave memoir Twelve Years a Slave by Solomon Northup, an African American man who was kidnapped in Washington, D.C. by two conmen in 1841 and sold into slavery. He was put to work on plantations in the state of Louisiana for 12 years before being released. The first scholarly edition of David Wilson's version of Northup's story was co-edited in 1968 by Sue Eakin and Joseph Logsdon.