STK19

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STK19
Identifiers
AliasesSTK19, D6S60, D6S60E, G11, HLA-RP1, RP1, serine/threonine kinase 19
External IDsMGI: 1860085 HomoloGene: 10449 GeneCards: STK19
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for STK19
Genomic location for STK19
Band6p21.33Start31,971,091 bp[1]
End31,982,821 bp[1]
RNA expression pattern
PBB GE STK19 36019 at fs.png

PBB GE STK19 204090 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004197
NM_032454

NM_019442

RefSeq (protein)

NP_004188
NP_115830

NP_062315

Location (UCSC)Chr 6: 31.97 – 31.98 MbChr 17: 34.82 – 34.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase 19 is an enzyme that in humans is encoded by the STK19 gene.[5][6][7]

This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants.[7]

References[edit]

  1. ^ a b c ENSG00000206342, ENSG00000236250, ENSG00000226033, ENSG00000204344, ENSG00000234947 GRCh38: Ensembl release 89: ENSG00000226257, ENSG00000206342, ENSG00000236250, ENSG00000226033, ENSG00000204344, ENSG00000234947 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061207 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Sargent CA, Anderson MJ, Hsieh SL, Kendall E, Gomez-Escobar N, Campbell RD (Jul 1994). "Characterisation of the novel gene G11 lying adjacent to the complement C4A gene in the human major histocompatibility complex". Hum Mol Genet. 3 (3): 481–8. doi:10.1093/hmg/3.3.481. PMID 8012361.
  6. ^ Gomez-Escobar N, Chou CF, Lin WW, Hsieh SL, Campbell RD (Dec 1998). "The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase". J Biol Chem. 273 (47): 30954–60. doi:10.1074/jbc.273.47.30954. PMID 9812991.
  7. ^ a b "Entrez Gene: STK19 serine/threonine kinase 19".

Further reading[edit]