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Protein S (Myxococcus xanthus)

Protein S is a protein found in Myxococcus xanthus. Its name derives from being the "S" band in an alphabetical ordering of proteins run from Myxococcus xanthus cell contents on a SDS-denaturing gel, its study was prompted by the huge increase in Protein S production during sporulation of Myxococcus xanthus. Though it has been purported as as 1994 that Protein S enables myxospores of Myxococcus xanthus higher resistance to endure heating, desiccation, UV radiation and sonication no such evidence exists; the work that cites claims no such evidence: Protein S is not essential for spore variability and resistance: protein S-deficient spores are viable and are as resistant to heat and sonication as complete spores. Protein S is structured into two domains; the two domains are homologous and have a Greek key structure. The domains share high similarity with other crystallin proteins. Protein S binds two 2 mol of calcium per mol of protein with a binding dissociation constant of 27 and 76 μM according to dialysis experiments.

In the same study mutagenesis experiments revealed arginine replacements to residue 40 or residue 129 can reduce the binding affinity. Since an NMR structure determine positions for the two binding sites at residues 10 and 71 and at residues 99 and 159. However, these binding sites were based on a cluster analysis of side-chain oxygen atoms and on results from site-directed mutagenesis studies and not yet experimentally verified. More an X-ray crystal structure on the truncated N-terminal domain revealed crystallographic evidence of two binding sites in the N-terminal domain; these binding sites are at residues 7,37,39 and 76 as well as at residues 36,77, 79, which agree with the mutagenesis experiments. However, if the N-terminal domain can bind two Ca2+ either only the N-terminal domain binds calcium, or, the full Protein S can bind more than two mol of calcium per mol of protein. Since both these claims have been experimentally shown to not be true the exact binding site of Protein S cannot yet be described

Farm to Market Road 960

Farm to Market Road 960 is a state highway in the U. S. state of Texas that stays within Wharton County. The two-lane road starts at Business Interstate 69 /Business U. S. Route 59-S northeast of El Campo, goes in a northerly direction through farmlands and ends at FM 102 at Glen Flora. FM 960 begins at Bus. 69/Bus 59 northeast of El heads to the northeast. Within a short distance the highway crosses Interstate 69 /U. S. Route 59 at an overpass. Connections with I-69/US 59 are complex. Southbound I-69/US 59 traffic desiring to access FM 960 must exit to a feeder road and use a special connecting road. Northbound I-69/US 59 traffic can use the Bus. 69/Bus 59 exit to access FM 960. To enter I-69/US 59 northbound, FM 960 traffic must take Bus. 69/Bus 59 north. To enter I-69/US 59 southbound, FM 960 traffic can use the special connecting road to the feeder, which leads to an entrance ramp. From Bus. 69/Bus 59, FM 960 heads to the northwest for 2.0 miles before turning to the northeast. After an additional 5.2 miles the highway comes to an intersection with FM 961 at the Wharton County Youth Fair Grounds.

From the fair grounds to the end of FM 960 at FM 102 in Glen Flora is 3.7 miles. In the last stretch, the highway turns to the southeast before veering back to the northeast and crossing the Colorado River. FM 960 was designated on November 23, 1948 to start at what is now I-69/US 59 a distance of 1.4 miles northeast of El Campo in Wharton County. From there the highway was to go north via Crescent School a total of 9.7 miles to a road intersection near the Colorado River. On July 14, 1949, FM 960 was extended about 1.5 miles across the Colorado River to Glen Flora. On June 30, 1976 the old US 59 right-of-way was redesignated Loop 525. On April 25, 1997, Loop 525 was canceled and its right-of-way transferred to Bus 59-S; the entire highway is in Wharton County. Texas portal U. S. Roads portal


SATREPS is a Japanese government program that promotes international joint research targeting global issues. The program is a collaboration between two Japanese government agencies: the Japan Science and Technology Agency and the Japan International Cooperation Agency. SATREPS projects are expected to lead to outcomes with potential for practical utilization, to enhance research capacity in the developing countries all around the world; some of the global challenges cannot be met by a single country or region acting on its own, so engagement by the international community is essential. To address these issues, SATREPS works through international projects by developing partnerships among researchers in Japan and researchers in developing countries. Distribution of ongoing projects SATREPS projects are selected each year from project proposals developed together with partner institutions in the developing countries and submitted by Japanese research institutions. In the four years since its commencements in April 2008, a total of 60 projects are in developed in 33 countries: The framework SATREPS projects are conducted through collaboration between JST and JICA.

JST uses research contracts to support research costs incurred inside Japan and some other locations excluding the country involved in the project. JICA provides support through its technical cooperation project framework to cover costs in the country involved in the collaborative project. Overall R&D management of the international joint research is handled jointly by JST, which has expertise in funding research projects at research institutions in Japan, JICA, which has expertise in technical cooperation in developing countries. SATREPS projects share the following characteristics: Joint research conducted for the purpose of resolving specific issues, where there is a strong need to enhance research capacity in the developing country involved in the project. Research with outcomes expected to contribute to both the developing country and the wider community. Research expected to contribute to the advancement of Japan's science and technologyPossible potential collaboration topics Research contributing to adaptation to climate change or mitigation of climate change Research contributing to the acquisition and treatment of safe water supplies Research contributing to the secure management of chemical risks Research contributing to the development of a closed-loop economy Research contributing to biodiversity and ecosystem conservation, including bio-remedies.

SATREPS Japan Science and Technology Agency, ja:科学技術振興機構

USNS Choctaw County (T-EPF-2)

USNS Choctaw County, is the second Spearhead-class expeditionary fast transport, part of the United States Military Sealift Command and was built in Mobile, Alabama. On 6 October 2011, Secretary of the Navy Ray Mabus announced in Ackerman, Mississippi that the second Expeditionary Fast Transport having been named Vigilant by the United States Army before the transfer of the EPF program to the Navy, would be named USNS Choctaw County. Since the ship will be operated by the Military Sealift Command and not the United States Navy itself, it will carry the USNS designation and not USS; the ship is named for three U. S. counties, located in Alabama and Oklahoma, all three of which are named for the Choctaw tribe of American Indians. The EPF can transport US Army and US Marine Corps company-sized units with their vehicles, or reconfigure to become a troop transport for an infantry battalion, it has a flight deck for helicopter operations and a loading ramp that allows vehicles to drive on and off the ship.

The ramp is suitable for quay walls common in developing countries. EPF has a shallow draft. Media related to IMO 9648001 at Wikimedia Commons

Siyabonga Cwele

Siyabonga Cyprian Cwele is a South African doctor and politician, a long-serving member of the African National Congress. He has held various ministerial positions and served as the Minister of Home Affairs from 2018 to 2019. Dr Cwele holds an MBChB Medical degree from the University of KwaZulu-Natal and an MPhil in Economic Policy from the University of Stellenbosch, he was previous the Minister of Telecommunications and Postal Services and served as the Minister of State Security. He has been a member of the ANC Provincial Executive Committee in KwaZulu-Natal since 1990, he served as Chairperson of the Joint Standing Committee on Intelligence and prior to his appointment as Minister of State Security, he served as Minister of Intelligence from 2008 to 2009. Cwele married his wife Sheryl in 1985 but by 2000 the marriage was estranged. Arrested in 2010, she was convicted of dealing or conspiring to deal in drugs, they divorced in 2011, they have four children together