Remembrancer was a British Thoroughbred racehorse and sire best known for winning the classic St Leger Stakes in 1803. Bred and trained in County Durham, he was still unnamed when winning six races including the St Leger and the Doncaster Cup as a three-year-old, was undefeated in four starts in 1804, including a division of the Great Subscription Purse at York Racecourse, he remained in training as a five-year-old, but failed to win. At stud, he was moderately successful as a sire of racehorses, but had a lasting impact on the breed through the success of his daughters as broodmares. Remembrancer was a bay horse bred by his owner John Bowes, 10th Earl of Strathmore and Kinghorne at Streatlam Castle in County Durham, his sire Pipator was a useful, but unremarkable racehorse who sired several good runners and broodmares. Remembrancer's dam, Queen Mab was a influential broodmare with many successful racehorses among her direct descendants, including Hill Prince, Indian Skimmer, King's Theatre and Henrythenavigator.
Until 1913, there was no requirement for British racehorses to have official names, the horse who became known as Remembrancer competed in 1803 as Lord Strathmore's b. c. by Pipator out of Queen Mab. Lord Strathmore's colt began his racing career on 13 April 1803 at Catterick Bridge Racecourse in Yorkshire where he had three engagements. In the opening race of the day he started 2/1 second favourite for a two-mile sweepstakes and won from Mr Hutton's chestnut colt; that afternoon he walked over for a 100 guinea match against Hutton's colt over the same distance, although the race was declared void. Lord Strathmore claimed another 100 guineas when Lord Darlington's bay colt failed to appear for a scheduled match against his the son of Pipator. In June, Lord Strathmore's colt ran in two races at Newcastle Racecourse in Northumberland. On the opening day he was made 1/3 favourite for a two-mile sweepstakes, but was beaten by William Walker's bay colt by Screveton. Three days Strathmore's colt was matched against older horses in the Newcastle Gold Cup over four miles, won from three opponents.
The colt next appeared at York Racecourse in August, where he upset the odds-on favourite Doncaster in a two-mile sweepstakes for three-year-olds. Two days the Strathmore's colt, finished second to Doncaster, but ahead of William Walker's colt, when the three met in a sweepstakes over one and three quarter miles at the same venue. On his next appearance, Strathmore's colt ran at Richmond Racecourse on 7 September, when he was beaten by Saxoni in a sweepstakes. On 27 September, Strathmore's colt was one of a field of eight runners to contest the twenty-eighth running of the St Leger over two miles at Doncaster, his rivals included Lord Grey's bay colt and Sir Frank Standish's brother to Stamford, horses which had finished second and third to Ditto in The Derby. Ridden by Ben Smith, Strathmore's colt started 5/2 favourite and won from Macmanus, with Lord Grey's colt in third place. On the following afternoon the Leger winner ran in the four mile Gold Cup and won the weight-for-age contest from Mr Garforth's bay colt and two others.
The colt earned a total of 1475 guineas for his owner in 1803. Lord Strathmore's colt, now named Remembrancer was undefeated in four races in the 1804 season, he made his first appearance of the year on 21 June in the Newcastle Gold Cup. He won the race for the second time, beating two others. In August, Remembrancer made two appearances both over a distance of four miles, he began by winning the Gold Cup from Mr Bowman's filly Susan, three days won division of the Great Subscription Purse, beating Mr Peirse's bay colt, with Doncaster in third. Remembrancer made his final appearance at Pontefract Racecourse on 11 September, he won a four-mile sweepstakes in which he conceded twenty-five pounds to a three-year-old named Sir Charles, his only opponent. Remembrancer's final season was affected by injury, he began his season at York in August where he started odds-on favourite for a division of the Great Subscription, but broke down injured in finishing second to Ferguson. His final appearance came in the Doncaster Cup of 25 September.
He was not fancied in the betting and showed none of his old form, finishing unplaced behind Lord Fitzwilliam's Caleb Quotem. Remembrancer was retired from racing to his at his owner's stud at Streatlam Castle, he began his breeding career in 1806 with five shillings for the groom. His fee rose to eight guineas in 1808, to ten guineas in 1810. Remembrancer moved to "the neighborhood of Northallerton" in 1811 and to Boroughbridge a year before returning to Streatlam Castle for the 1816 season. After this time he appears to have produced few more foals and his name ceased to appear in the lists of stallion advertisements. Remembrancer died on 3 February 1829 at the age of twenty-nine. Remembrancer sired several good racehorses including the Craven Stakes winner Recordon, but had his greatest success as a sire of broodmares, his most enduring influence came through an unnamed "Remembrancer mare" foaled in 1807, who became the Foundation mare of Thoroughbred family 8-f. Her direct, female-line descendants have won many important races throughout the nineteenth and twenty-first centuries including the British Classic winners Nijinsky, El Gran Senor and The Minstrel as well as the notable North American runners Blue Larkspur, Rags to Riches
Evelyne Accad is a Lebanese-born educator and writer living in the United States and Lebanon. Accad is a father of Lebanese and Egyptian descent, she was born in Beirut in 1943 and grew up in Lebanon and came to the United States in the early 1960s. She was educated at the Beirut College for Women, Anderson College, Ball State University and Indiana University Bloomington, receiving a PhD in comparative literature from the latter institution. Accad taught at Beirut University College in 1978 and 1984 and at Northwestern University in 1991, she is Professor Emerita in Francophone, African, Middle East, Women's Studies and Comparative Literature at the University of Illinois at Urbana–Champaign and the Lebanese American University in Beirut. She published her first novel L'Excisée in 1982; this novel deals with excision of women in both the metaphorical sense. Although she has her own unique style, Accad was influenced by the Egyptian-born French writer Andrée Chedid and the Egyptian writer Nawal El Saadawi.
Coquelicot du massacre Blessures des Mots: Journal de Tunisie.
James Samuel Malosky Sr. was an American football coach. He ranks 18th all-time in wins among college football coaches in all divisions, he was the head football coach at the University of Minnesota Duluth for 40 years from 1958 to 1997. He compiled a career record of 255–125–13 and is ranked second all-time in wins among NCAA Division II football coaches. Malosky was a native of Crosby, who began his coaching career at Morris and Morningside-Edina High Schools, he was hired as the head football coach at University of Minnesota Duluth in 1958 and led the team to Minnesota Intercollegiate Athletic Conference championships in 1960, 1961 and 1973. In 1976, the school joined the Northern Sun Intercollegiate Conference. Malosky led the team to eight Northern Sun championships, in 1979, 1980, 1985, 1986, 1987, 1990, 1995, 1996. Malosky's 1980 team compiled a perfect 10–0 record, part of a 20-game winning streak, which "at the time was the longest in all of college football."Malosky was forced to retire due to health concerns.
Malosky had never missed practice, or teaching assignment in 40 years. However, in May 1998, he suffered a mild stroke, he recovered from the stroke sufficiently to attend practices and games in the fall of 1998, but he realized that he "couldn't run the ship the way he had in the past."At the time of his retirement, he was the winningest coach in NCAA Division II football history and ranked 11th among all college football coaches in all divisions. As of 2008, he ranked 2nd among NCAA Division II coaches and 18th among all college football coaches in all divisions. Malosky was inducted into the Minnesota High School Football Coaches Association Hall of Fame in 1994, the University of Minnesota Hall of Fame in 1996, the University of Minnesota Duluth Athletic Hall of Fame in 1999, the Northern Sun Intercollegiate Athletic Conference Hall of Fame in 2000. In 2004, the University of Minnesota Duluth renamed its football stadium in Malosky's honor as James S. Malosky Stadium; the stadium underwent a $6.5 million renovation in 2008.
At a nationally televised game on September 11, 2008, the stadium was dedicated to Malosky. Malosky received a standing ovation from the crowd. In 2009, Malosky received the Distinguished Minnesotan Award by the Minnesota Chapter of the National Football Foundation and the College Football Hall of Fame; the award is given to individuals who have made a lifelong contribution to football in the state of Minnesota. The Jim Malosky Coach of the Year Award, named after Malosky, is given annually to the Division II Coach of the Year, he died December 2011 due to respiratory failure. List of college football coaches with 200 wins
Louis Ptáček is an American neurologist and professor who contributed to the field of genetics and neuroscience. His chief areas of research include the understanding of inherited Mendelian disorders, circadian rhythm genes. Ptáček is a neurology professor and a director of the Division of Neurogenetics in University of California, San Francisco, School of Medicine, his current investigations focus on extensive clinical studies in families with hereditary disorders which include identifying and characterizing the genes responsible for neurological variations. In 1982, Louis Ptáček earned his Bachelor of Science degree in mathematics from the University of Wisconsin-Madison. In 1986, he received his Doctor of Medicine degree from the University of Wisconsin-Madison Medical School. During his neurology residency at University of Utah, he met a 28-year-old female patient, suffering from sporadic paralysis, that inspired his current interest in the research of genetic diseases and episodic disorders.
In 1991, he discovered that a mutation in a gene that coded for a muscle cell sodium channel caused the patient's condition, hyperkalemic periodic paralysis. As the first channel discovered to cause human disease, this human skeletal muscle sodium channel prevented the muscle from proper contractions; this invoked a series of discoveries of mutant ion channel genes which constructed the framework for studying similar diseases, which Ptáček calls "channelopathies."In 1999, Christopher Jones, a neurologist from University of Utah who specializes in sleep disorders, contacted Ptáček to characterize a family of early risers and find the genes associated with this phenotype. He and his partner, Ying-Hui Fu, in collaboration with Jones, have identified multiple genes, such as hPer2, that are responsible for familial advanced sleep phase syndrome; this discovery prompted Ptáček to continue his research on circadian genes. Ptáček began his research on episodic neurological diseases by cloning and identifying genes that were responsible for periodic paralysis and non-dystrophic myotonia.
His research focuses on determining episodic disorders of the muscle and brain, found that many episodic diseases result from mutations in the electrical signaling of cell membranes. He had a large role in discovering that hyperkalemic periodic paralysis, paramyotonia congenita, Andersen-Tawil syndrome, thyrotoxic periodic paralysis are caused by mutations in genes encoding for voltage gated ion channels, his current research focuses on identifying the genes involved with Andersen-Tawil syndrome. Ptáček's lab have identified KCNJ2 mutations to be responsible for this syndrome, but due to the intrafamilial variability among the mutations, they hope to identify and characterize this gene further, thus far, Ptáček and his colleagues have identified six disease-causing mutations, five of which are dominant negative mutations that mask the wild-type allele, resulting in a loss-of-function of that gene. With his continued research on ATS, Ptáček has discovered and identified additional phenotypic diagnostic criteria for ATS using skeletal and dental findings.
Additionally, he has identified other markers of the KCNJ2 channel mutation's including its ECG outputs' T-Wave and U-Wave patterns in order to provide more accurate differential diagnosis from Long QT Syndrome. Ptáček, with a team of collaborators, hypothesized that thyrotoxic periodic paralysis may be a case of channelopathy and can arise from ion channel mutations that display symptoms with hyperthyroidism. In January 2010, they discovered a gene that encodes Kir2.6, a novel inwardly rectifying potassium channel. This protein channel similar to Kir2.2, is transcriptionally regulated by the thyroid hormone and expressed in skeletal muscles. Kir2.6 mutations, found in one third of unrelated TPP patients in the initial study, affect muscle membrane excitability and can lead to periodic paralysis. In 1999, Ptáček was introduced to a family in Utah who had a distinct sleep schedule. After analyzing the family's pedigree and identifying individuals with a genetic basis for an advanced sleep phase, he coined the term familial advanced sleep phase syndrome.
The disorder is characterized by around a four-hour phase advance, causing individuals to sleep from 7:30 pm to 4:30 am. In 2001, Ptáček and his colleagues discovered the mutation in the autosomal dominant allele responsible for FASPS; the point mutation is in the hPer2 gene, results in a serine to glycine amino acid substitution at position 662. Specially, this mutation occurs in the CK1ε binding region of the PER2 protein, causes PER2 to be hypophosphorylated in that region, allowing it to be more stable and enter the nucleus faster; this results in quicker suppression of the hPer2 gene transcription, shortening the individual's circadian period and leading to FASPS symptoms. Ptáček and his colleagues have found that hPer2 is not the only gene that causes FASPS when mutated, current research is exploring other sporadic cases of FASPS to identify new mutations that contribute to the syndrome. Ptáček's lab is interested in studying the genetic basis of familial delayed sleep phase syndrome, a condition characterized by a delay in the sleep cycle where affected individuals fall asleep late in the night and wake up late in the morning or afternoon.
Thus far, little is known about FDSPS although it is thought to be a heritable condition common in adolescents with symptoms subsiding with age. However, some individuals are affected by FSDPS throughout their lives. Toh KL, Jones CR, He Y, Eide EJ, Hinz WA, Virshup DM, Ptáček LJ, Fu Y-H. An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep-Phase Syndrome. Science. 2001.
Aloysius Arabao Iyomogo Edrick Amwano is a Nauruan politician. Amwano started his parliamentary career in 1998, when he won a vacated seat in a by-election for the Ubenide Constituency following the resignation of former president Lagumot Harris. In the 2000 general elections he was re-elected, he was the Speaker of the Parliament of Nauru from 29 March 2001 to 30 March 2001. After the 2003 general elections he lost his seat to Fabian Ribauw. In 2008 he was re-elected to parliament, he became part of President Marcus Stephen's parliamentary majority, before switching over to the opposition in 2010. He was one of three non-Cabinet government MPs to switch to the opposition after benefiting from a trip to Singapore organised and paid for by the Australian company Getax, which buys Nauruan phosphate. Getax had just sought, unsuccessfully, to propose a loan to the Stephen government, with contractual clauses enabling it to take over Nauru's phosphate industry in the event that the government defaulted in repaying.
Following the Getax-funded trip and two other MPs withdrew their support for the government, joining the opposition and causing Parliament to be evenly split between government and opposition MPs. This resulted in fresh parliamentary elections in April 2010. On 30 June 2010, he was elected Speaker, demanded that Stephen stand down as president. On 6 July, opposition MP Rykers Solomon joined the government giving it the numbers to re-elect Stephen, or to elect a new president from within its ranks; as Speaker, Amwano refused to allow the election for president to be held. Amwano refused to relinquish his post. In a short parliamentary session held on 9 July, Deputy Speaker Landon Deireragea announced that he had assumed the Speaker's position in Amwano's place. In October, the Nauruan government accused Getax of having paid significant sums of money to opposition MPs, of having funded the opposition's election campaign; the Australian Federal Police investigated the allegations that Getax had bribed Nauruan MPs "to influence the political regime in Nauru in order to increase their stake in the country's phosphate".
Amwano spoke up to defend Getax, denying any wrongdoing and adding that he "would be happy for the Australian Federal Police to investigate". Amwano was defeated in the 2013 elections, was replaced by Ranin Akua. Politics of Nauru Elections in Nauru 2008 Nauruan parliamentary election April 2010 Nauruan parliamentary election