Secnidazole

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Secnidazole
Secnidazole.svg
Clinical data
Trade names Solosec
Synonyms PM 185184, RP 14539
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.020.123 Edit this at Wikidata
Chemical and physical data
Formula C7H11N3O3
Molar mass 185.180 g/mol
3D model (JSmol)
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Secnidazole (trade names Flagentyl, Sindose, Secnil, Solosec) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported.[1] It has also been tested against Atopobium vaginae.[2]

On the United States, secnidazole is approved for the treatment of bacterial vaginosis in adult women.[3]

References[edit]

  1. ^ Girginkardeşler, N.; Coşkun, S.; Cüneyt Balcioğlu, I.; Ertan, P.; Ok, U. Z. (2003). "Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole". Clinical Microbiology and Infection. 9 (2): 110–113. doi:10.1046/j.1469-0691.2003.00504.x. PMID 12588330. 
  2. ^ De Backer, E.; Dubreuil, L.; Brauman, M.; Acar, J.; Vaneechoutte, M. (2009). "In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis". Clinical Microbiology and Infection. 16 (5): 470–472. doi:10.1111/j.1469-0691.2009.02852.x. PMID 19548924. 
  3. ^ "FDA Approves Symbiomix Therapeutics' Solosec (secnidazole) Oral Granules for the Treatment of Bacterial Vaginosis in Adult Women" (Press release). Symbiomix Therapeutics. 

External links[edit]

  • Gillis, J. C.; Wiseman, L. R. (1996). "Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis". Drugs. 51 (4): 621–38. doi:10.2165/00003495-199651040-00007. PMID 8706597.