The siege of Rouen was a key military engagement of the first French War of Religion. After having been seized by those opposing the crown on 16 April, the siege, beginning on 28 May and culminating on 26 October brought the important city of Rouen back into the crowns control. The fall of Rouen would set the stage for the main battle of the war at Dreux several months later.

Charles IX was King of France from 1560 until his death in 1574. He ascended the French throne upon the death of his brother Francis II in 1560, and as such was the penultimate monarch of the House of Valois.