SUMMARY / RELATED TOPICS

Sigma-Aldrich

Sigma-Aldrich Corporation is an American chemical, life science and biotechnology company owned by Merck KGaA. Created by the 1975 merger of Sigma Chemical Company and Aldrich Chemical Company, Sigma-Aldrich since grew through various acquisitions until it had over 9,600 employees and was listed on the Fortune 1000 at the time of its acquisition by Merck; the company is headquartered in St. Louis and has operations in 40 countries. In September 2014, the German company Merck KGaA announced that it would be acquiring Sigma-Aldrich for $17 billion; the acquisition was completed in November 2015 and Sigma-Aldrich became a subsidiary of Merck KGaA. The company is a part of Merck's life science business and in combination with Merck's earlier acquired Millipore, operates as MilliporeSigma. Sigma Chemical Company of St. Louis and Aldrich Chemical Company of Milwaukee were both American specialty chemical companies when they merged in August 1975; the company grew throughout the 1980s and 1990s, with significant expansion in facilities and diversification into new market sectors.

1935 – Midwest Consultants was founded in St Louis by the Fischer brothers. 1946 – Sigma was formed from Midwest Consultants and manufactured just adenosine triphosphate. They were the first to manufacture pure ATP. 1972 – Sigma's IPO 1951 – Aldrich founded in Milwaukee by Alfred Bader and Jack Eisendrath and manufactured just 1-methyl-3-nitro-1-nitrosoguanidine. 1966 – Aldrich's IPO 1972 – Subsidiary Aldrich-Boranes launched to manufacture hydroboration products 1975 – Merger of Sigma Chemical and Aldrich Chemical to created Sigma-Aldrich. Their first year earned $43 million in sales. 1999 – Sigma-Aldrich reaches $1 billion in sales 2005 – Announced membership in The RNAi Consortium 2014 – Merck KGaA announced that it would purchase Sigma-Aldrich for approx. $17 billion. November 3, 2014 – Sigma-Aldrich filed a definitive proxy statement with the U. S. Securities and Exchange Commission to hold a special investors meeting regarding approval for the sale to Merck KGaA. 1978 – Makor Chemicals 1984 – Pathfinder 1986 – Bio Yeda, Bristol Organics 1989 – Fluka Chemie AG purchased for $39 million.

1993 – Supelco, Inc. acquired to enter the chromatography market 1994 – LabKemi AB 1997 – Research Biochemicals International, Riedel-de-Haen, Techcares Systems, Carbolabs, YA Kemia 1998 – Genosys 2000 – First Medical Inc. Amelung GmbH, ARK Scientific 2001 – ISOTEC 2004 – Ultrafine, Tetrionics 2005 – JRH Biosciences, an industrial supplier of cell culture products for the pharmaceutical and biotechnology industries. BioReliance. 2014 – Cell Marque 2015 – Combined with EMD Millipore to make MilliporeSigma. Key numbers for Sigma-Aldrich. Revenues: $2.79 billion Products: 100,000 chemical products 30,000 laboratory equipment productsCustomers: Approximately one million individual customers worldwide 88,000 accountsGeographies: United States 35% Europe 43% Canada, Asia Pacific, Latin America 22% Aldrich is a supplier in the research and fine chemicals market. Aldrich provides organic and inorganic chemicals, building blocks, advanced materials and stable isotopes for chemical synthesis, medicinal chemistry and materials science.

Aldrich's chemicals catalog, the "Aldrich Catalog and Handbook" is used as a handbook due to the inclusion of structures, physical data, literature references. Sigma is the Sigma-Aldrich's main biochemical supplier, with offerings including antibiotics, carbohydrates, forensic tools and histology, proteins, amino acids and their derivatives. Sigma RBI produces specialized products for use in the field of cell neuroscience, their offerings range from standard biochemical reagents to specialized research tools, including ligands for receptors and ion channels, enzyme inhibitors, phosphospecific antibodies, key signal transduction enzymes, assay kits for cell signaling. ISOTEC provides isotopically labeled products for protein structure determination, peptide synthesis, metabolic research, magnetic resonance imaging, nuclear magnetic resonance, breath test substrates, agriculture, as well as gas and gas mixes. Riedel-de Haën manufactures reagents and standards. Supelco is the chromatography products branch of Sigma-Aldrich.

It provides chromatography columns and related tools for environmental, government and beverage, biotechnology and chemical laboratories. Sigma-Aldrich Fine Chemicals is the fine chemical supply branch of Sigma-Aldrich specializing in raw materials for cell culture products.

Significant acts of violence against LGBT people

This is a list of notable homophobic and transphobic violence. Examples include corrective rape and other types of assault. See list of unlawfully killed transgender people for homicides of transgender people. In 1972, George Duncan and Roger Jones were thrown into a river in Adelaide by a group of men believed to be police officers, resulting in Duncan's death. Jones refused to identify their attackers out of fear for his life. Two police officers were charged but acquitted, the case was said to have been the subject of a government cover-up. An independent police report described it as the result of a "'high-spirited frolic' that went wrong". In January 1987, Raymond Keam was killed in Alison Park, Sydney, his injuries were consistent with attackers having jumped on his chest. In December 1988, Scott Johnson's body was found at the bottom of a 50-metre cliff near Blue Fish Point around Manly, Sydney. There have been many investigations into the cause of this death; the police had described his death as suicide, but a 2017 inquest — the third on his death — admitted he was murdered in an anti-gay hate crime.

In January 1989, Richard Johnson was lured to a toilet block in Alexandria Park, Sydney where he had left his phone number on the wall where he was gang bashed to death. In July 1989, after a night drinking with friends on Oxford Street in Sydney, Ross Warren's keys were found at the base of the cliffs at Tamarama, his car was nearby, his body was never found. In November 1989, John Russell was found at the bottom of Marks Park.

Gaby oh Gaby

"Gaby oh Gaby" is a song first published by Alain Bashung. Written by Boris Bergman with music by Bashung, it was published as a single in 1980 on Philips, with "Elle s'fait rougir toute seule" as the B-side; the single became a huge hit in France, therefore the song was included on the album Roulette russe in a reissue nicknamed Nouveau couplage, on the CD reissue of the next album, Pizza. When the single came out, Bashung had been a singer for fourteen years; the singles recorded between 1966 and 1977 were all commercial failures and his first album, Roman-photos, issued in 1977, which he would disown, was one as well. "Gaby oh Gaby" revealed the singer to a larger audience. The song was shown in numerous TV shows on the evening and during the night, broadcast on radio, was in first page of the newspaper Libération; however if he admits that this hit saved him at the time, Bashung was caught off-guard by this unexpected success. On the album Play blessures issued in 1982, Bashung sang about this on his song "J'croise aux hybrides": "J'dédie cette angoisse à un chanteur disparu, mort de soif dans le désert de « Gaby ».

Respectez une minute de silence, faites comme si j'étais pas arrivé..." On May 19, 2009, the Gold Disc of the original 45rpm was sold on auction in Paris by its owner, a collector. It was sold for €3717; the song is included in a list of 3000 rock classics in the book La Discothèque parfaite de l'odyssée du rock by Gilles Verlant, who calls the track "Gaby oh Gaby" one of the "summits of the decade" alongside the next single "Vertige de l'amour". Boris Bergman, the lyricist, explained after the death of Alain Bashung: "C’est un texte sur les minorités, ceux que «la différence» fait tomber dans les puits de solitude. Le petit Ashkénaze que je suis, le Kabylo-Alsacien qu’est Alain, s’en doutent depuis leur première rencontre avec l’autre: "Gaby" est aussi un hymne caché à la solitude de l’homo qui ne connaît pas encore l’existence du PACS."