St Mary's Church in Cheadle, Greater Manchester, England, is a Grade I listed building. It is an Anglican parish church in the diocese of Chester, the archdeaconry of Macclesfield and the deanery of Cheadle. Its benefice is united with that of St Cuthbert.

Cheadle is a village in the Metropolitan Borough of Stockport, Greater Manchester, England. Within the boundaries of the historic county of Cheshire, it borders Cheadle Hulme, Gatley, Heald Green and Cheadle Heath in Stockport, and East Didsbury in Manchester. In 2011, it had a population of 14,698.