Street of Chance is a 1930 American pre-Code film directed by John Cromwell and starring William Powell, Jean Arthur, Kay Francis and Regis Toomey. Howard Estabrook was nominated for the Academy Award for Best Writing, Achievement.

John Cromwell was an American film and stage director and actor. His films spanned the early days of sound to film noir in the early 1950s, by which time his directing career was almost terminated by the Hollywood blacklist.