Sulfolactate sulfo-lyase

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Sulfolactate sulfo-lyase
EC number
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a sulfolactate sulfo-lyase (EC, Suy, SuyAB, 3-sulfolactate bisulfite-lyase, sulfolactate sulfo-lyase) is an enzyme that catalyzes the chemical reaction

3-sulfolactate pyruvate + bisulfite

Hence, this enzyme has one substrate, 3-sulfolactate, and two products, pyruvate and bisulfite.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is 3-sulfolactate bisulfite-lyase (pyruvate-forming). Other names in common use include Suy, SuyAB, and 3-sulfolactate bisulfite-lyase.[1][2][3]


  1. ^ Graham DE, White RH (April 2002). "Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics". Natural Product Reports. 19 (2): 133–47. doi:10.1039/b103714p. PMID 12013276. 
  2. ^ Rein U, Gueta R, Denger K, Ruff J, Hollemeyer K, Cook AM (March 2005). "Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA". Microbiology. 151 (Pt 3): 737–47. doi:10.1099/mic.0.27548-0. PMID 15758220. 
  3. ^ Denger K, Cook AM (March 2010). "Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase". Microbiology. 156 (Pt 3): 967–74. doi:10.1099/mic.0.034736-0. PMID 20007648.