The Real World: Key West is the seventeenth season of MTV's reality television series The Real World, which focuses on a group of diverse strangers living together for several months in a different city each season, as cameras follow their lives and interpersonal relationships. It is the second season of The Real World to be filmed in the South Atlantic States region of the United States, specifically in Florida after The Real World: Miami.

The Real World is an American reality television series produced through MTV and Bunim/Murray Productions that most recently aired on Facebook Watch after airing on MTV from 1992 to 2017, and was originally produced by Mary-Ellis Bunim and Jonathan Murray. First broadcast in 1992, the show, which was inspired by the 1973 PBS documentary series An American Family, is the longest-running program in MTV history, one of the longest-running reality series in history, and is credited with launching the modern reality TV genre. Seven to eight young adults are picked to temporarily live in a new city together in one residence while being filmed non-stop.