Thornbury railway station is a commuter railway station on the Mernda line, serving the north-eastern Melbourne suburb of Thornbury, Victoria, Australia. Thornbury is an unstaffed status ground structure station featuring two side platforms. It opened on 8 October 1889.

The Mernda line is a commuter railway line in the city of Melbourne, Victoria, Australia. Operated by Metro Trains Melbourne, it is the city's eighth longest metropolitan railway line at 33.1 kilometres (20.6 mi). The line runs from Flinders Street station in central Melbourne to Mernda station in the north, serving 29 stations including Clifton Hill, Reservoir, Epping, and South Morang. The line operates for approximately 19 hours a day with 24-hour service available on Friday and Saturday nights. During peak hour, headways of up to 7.5 minutes are operated with services every 10–30 minutes during off-peak hours. Trains on the Mernda line run with two three-car formations of X'Trapolis 100 trainsets.