Thunberginol A

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Thunberginol A
Chemical structure of thunberginol A
Names
IUPAC name
3-(3,4-dihydroxyphenyl)-8-hydroxyisochromen-1-one
Identifiers
3D model (JSmol)
ChemSpider
Properties
C15H10O5
Molar mass 270.24 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYNo ?)
Infobox references

Thunberginol A is an isocoumarin found in Hydrangea macrophylla[1] and the herbal preparation hydrangeae dulcis folium which is produced from its leaves.[2][3]

References[edit]

  1. ^ Matsuda, H.; Shimoda, H.; Yamahara, J.; Yoshikawa, M. (1999). "Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols a and F from Hydrangea macrophylla SERINGE var. Thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats". Biological & Pharmaceutical Bulletin. 22 (8): 870–872. doi:10.1248/bpb.22.870. PMID 10480329. INIST:1959604. 
  2. ^ Yamahara, J.; Matsuda, H.; Shimoda, H.; Wariishi, N.; Yagi, N.; Murakami, N.; Yoshikawa, M. (1995). "Effects of thunberginol a contained in Hydrangeae dulcis forium on types I-IV allergies". Nihon yakurigaku zasshi. Folia pharmacologica Japonica (in Japanese). 105 (5): 365–379. PMID 7628785. 
  3. ^ Matsuda, H.; Shimoda, H.; Yamahara, J.; Yoshikawa, M. (1998). "Immunomodulatory activity of thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens". Bioorganic & Medicinal Chemistry Letters. 8 (3): 215. doi:10.1016/S0960-894X(97)10221-9.