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Clinical data
Synonyms 1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, Threitol 1,4-dimethanesulfonate, Threitol 1,4-bismethanesulfonate; L-Threitol 1,4-bis(methanesulfonate); Ovastat; Threosulphan; Treosulphan; Tresulfan
AHFS/ International Drug Names
Routes of
Oral, IV
ATC code
CAS Number
PubChem CID
ECHA InfoCard 100.005.529 Edit this at Wikidata
Chemical and physical data
Formula C6H14O8S2
Molar mass 278.30056 g·mol−1
3D model (JSmol)
Melting point 101.5 to 105 °C (214.7 to 221.0 °F)
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Treosulfan is a substance that is being studied in the treatment of cancer.[1] It belongs to the family of drugs called alkylating agents. It has been used mainly as a substitute of busulfan in frail patients, as the side effects and toxicity are supposedly less severe.


  1. ^ Schmittel A, Schmidt-Hieber M, Martus P, et al. (December 2006). "A randomized phase II trial of gemcitabine plus treosulfan versus treosulfan alone in patients with metastatic uveal melanoma". Ann. Oncol. 17 (12): 1826–9. doi:10.1093/annonc/mdl309. PMID 16971664.

External links[edit]

  • Treosulfan entry in the public domain NCI Dictionary of Cancer Terms

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".