Trimble County is a county located in the north central part of the U.S. state of Kentucky. Its county seat is Bedford. The county was founded in 1837 and is named for Robert Trimble. Trimble is no longer a prohibition or dry county. Trimble County is part of the Louisville/Jefferson County, KY–IN Metropolitan Statistical Area.

Robert Trimble was a lawyer and jurist who served as Justice of the Kentucky Court of Appeals, as United States district judge of the United States District Court for the District of Kentucky and as Associate Justice of the Supreme Court of the United States from 1826 to his death in 1828. During his brief Supreme Court tenure he authored several majority opinions, including the decision in Ogden v. Saunders, which was the only majority opinion that Chief Justice John Marshall ever dissented from during his 34 years on the Court.