USS Guadalcanal (CVE-60) was a Casablanca-class escort carrier of the United States Navy, which served during and after World War II. She was the first ship to carry her name. She was the flagship of Task Group 22.3, a hunter-killer group which captured the German submarine U-505 in 1944.

The Casablanca-class escort carrier was a series of escort carriers constructed for the United States Navy during World War II. They are the most numerous class of aircraft carriers ever built. Fifty were laid down, launched and commissioned within the space of less than two years – 3 November 1942 through to 8 July 1944. Despite their numbers, and the preservation of more famous and larger carriers as museums, none of these modest ships survive today. Five were lost to enemy action during World War II and the remainder were scrapped.