Vestibular papillomatosis

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Vestibular papillomatosis

Vestibular papillomatosis (VP) is a cutaneous condition of the vulva, characterized by pink, asymptomatic, fine projections of the vestibular epithelium or labia minora.[1] It is the female equivalent to hirsuties coronae glandis.[2][3] It is often thought to be a human papillomavirus (HPV) infection, but several studies have shown that the condition is not viral and is not a sexually transmitted disease (STD).

DNA studies have shown that any relation to HPV is purely coincidental (as a high percentage of the sexually active population has or has had HPV).[4] Vestibular papillomatosis is not transmittable or pathological. HPV will turn white upon a vinegar application test, and vestibular papillomatosis will not. Additionally, HPV occurs in cauliflower-like clusters at the base, whereas Vestibular papillomatosis does not. It cannot be sexually transmitted.[5] Most women have no symptoms with the growth; however, some report itching, stinging, burning, and pain where the growths appear, and the symptoms are often misdiagnosed as a yeast infection. Like yeast infections, there is discharge associated with vestibular papillomatosis.[6][7][8] The condition is sometimes referred to as squamous papillomatosis.

There is some evidence that (VP) may be congenital; however, these cases are extremely rare.[9]

See also[edit]


  1. ^ noSu-Han Kim; et al. (February 2009). "The use of dermatoscopy to differentiate vestibular papillae, a normal variant of the female external genitalia, from condyloma acuminata". Journal of the American Academy of Dermatology. 60 (2): 353–355. doi:10.1016/j.jaad.2008.08.031. PMID 19150287. Retrieved 2014-07-12. 
  2. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  3. ^ "MMS: Error". Retrieved 2014-07-12. 
  4. ^ Fimiani M, Mazzatenta C, Biagioli M, Andreassi L. "Vulvar squamous papillomatosis and human papillomavirus infection. A polymerase chain reaction study". Arch Dermatol Res. 285 (5): 250–4. doi:10.1007/bf00371592. PMID 8397492. 
  5. ^ Moyal-Barracco M, Leibowitch M, Orth G (1990). "Vestibular papillae of the vulva. Lack of evidence for human papillomavirus etiology". Arch Dermatol. 126 (12): 1594–8. doi:10.1001/archderm.1990.01670360058008. PMID 2175164. 
  6. ^ "Vestibular Papillomatosis: Case Report and Literature Review- Full HTML - Acta Dermato-Venereologica - Content". Retrieved 2014-07-12. 
  7. ^ "An Error Occurred Setting Your User Cookie". Retrieved 2014-07-12. 
  8. ^ "Sexually Transmitted Diseases: Are these genital warts? Please help!, pearly penile papules, genital warts". Retrieved 2014-07-12. 
  9. ^ [1]