Vitisin A (stilbenoid)

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Vitisin A
Chemical structure of vitisin A
Names
Other names
R2-Viniferin[1]
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
Properties
C56H42O12
Molar mass 906.92 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Vitisin A is a resveratrol tetramer found in plants of the genus Vitis. It is a complex of two resveratrol dimers, (+)-epsilon-viniferin and ampelopsin B.[2]

It shows an opposite effect to hopeaphenol on apoptosis of myocytes isolated from adult rat heart.[2][3][4]

References[edit]

  1. ^ Poster at 1st International Conference of Resveratrol and Health, Jean-Claude Izard, 2010
  2. ^ a b Seya, K.; Kanemaru, K.; Sugimoto, C.; Suzuki, M.; Takeo, T.; Motomura, S.; Kitahara, H.; Niwa, M.; Oshima, Y.; Furukawa, K. -I. (2008). "Opposite Effects of Two Resveratrol (trans-3,5,4'-Trihydroxystilbene) Tetramers, Vitisin a and Hopeaphenol, on Apoptosis of Myocytes Isolated from Adult Rat Heart". Journal of Pharmacology and Experimental Therapeutics. 328 (1): 90–98. doi:10.1124/jpet.108.143172. PMID 18927354.
  3. ^ Kim, S. H.; Park, H. S.; Lee, M. S.; Cho, Y. J.; Kim, Y. S.; Hwang, J. T.; Sung, M. J.; Kim, M. S.; Kwon, D. Y. (2008). "Vitisin a inhibits adipocyte differentiation through cell cycle arrest in 3T3-L1 cells". Biochemical and Biophysical Research Communications. 372 (1): 108–113. doi:10.1016/j.bbrc.2008.04.188. PMID 18482581.
  4. ^ Mi Jeong Sung, S.; Davaatseren, M.; Kim, W.; Sung Kwang, P.; Kim, S. H.; Haeng Jeon, H.; Myung Sunny, K.; Kim, Y. S.; Dae Young, K. (2009). "Vitisin a suppresses LPS-induced NO production by inhibiting ERK, p38, and NF-κB activation in RAW 264.7 cells". International Immunopharmacology. 9 (3): 319–323. doi:10.1016/j.intimp.2008.12.005. PMID 19135555. INIST:21253190.

External links[edit]