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Wheeler Peak (New Mexico)

Wheeler Peak is the highest natural point in the U. S. state of New Mexico. It is located northeast of Taos and south of Red River in the northern part of the state, just 2 miles southeast of the ski slopes of Taos Ski Valley, it lies in the southernmost subrange of the Rocky Mountains. The peak's elevation is 13,167 feet. Named Taos Peak, after the nearby town of Taos, New Mexico, it was renamed Wheeler Peak in 1950. A plaque at the summit states that the mountain was: Named in honor of Major George Montague Wheeler who for ten years led a party of surveyors and naturalists collecting geologic, biologic and topographic data in New Mexico and six other southwestern states. Just north of Wheeler Peak is Mount Walter. At 13,141 feet it is the second highest named summit in New Mexico, but it is not considered an independent peak as it has only about 53 feet of topographic prominence, it is sometimes mistaken for Wheeler Peak. Lake Fork Peak at 12,881 feet lies just to the west of Wheeler Mountain.

Taos Ski Valley lies to the northwest of Wheeler Peak, while both the town of Taos and Taos Pueblo are about 15 miles to the southwest. Wheeler Peak is the focus of the 19,661-acre Wheeler Peak Wilderness area in the Carson National Forest. Much of the mountain area just south of the peak is on Taos Pueblo land; some 48,000 acres was returned to the pueblo from the Carson National Forest in 1970 and another 764 acres in 1996. The standard route on Wheeler Peak is along the north ridge; the route starts at the parking lot for Taos Ski Valley, proceeds east along an old road to a broad saddle at Bull-of-the-Woods Meadow. It turns south and winds its way among minor peaks and small valleys to gain Wheeler Peak from the north, going over the summit of Mount Walter along the way; this is a practical route in winter, due to low avalanche exposure. An alternate route is to hike south from Taos Ski Valley to Williams Lake take a newly constructed switchback trail to the top; this trail was completed in 2011 by a Forest Service trail crew from the Gallatin National Forest, 8 people working 12 hours per day, building 4 miles of new trail with hand tools to the top in 14 days.

Another alternate route is to begin from the nearby ski resort of Red River. From the town of Red River drive 6.4 miles south on NM 578 1.3 miles on FR 58 to the trailhead parking area. From the parking area Wheeler peak is about 7 miles on Forest Trail 91; this route passes Lost Lake and Horseshoe Lake. Wheeler Peak has a summit. List of mountain peaks of North America List of mountain peaks of the United States List of U. S. states by elevation "Wheeler Peak". SummitPost.org. "Wheeler Peak Wilderness". U. S. Forest Service

Robert Heard

Robert Lee Heard was an American writer and reporter for the Associated Press, who covered politics and sports news in Texas for the wire service. Heard was shot and wounded by Charles Whitman on August 1, 1966, while covering Whitman's attack on the University of Texas at Austin for the Associated Press. Heard received widespread praise for his series of reports on the integration of the Texas Longhorns football team, he authored several books, focusing on sports and politics. Robert Heard was born in April 1930, in Big Spring, Texas, his father was a Baptist preacher. He had three older brothers. Heard's parents, who had expected a baby girl, did not know, they decided to call him Robert Lee after General Robert E. Lee, at the urging of his two older brothers, who had just learned about the Civil War general in elementary school. Heard served in the United States Marines in the Korean War from 1951 to 1952, he returned to Texas after the war. He practiced law in Houston for two years before pursuing a career change to journalism.

He worked as a journalist at the Waco Tribune-Herald in Waco and the AP Long Beach, California. Heard was hired as a reporter by the Associated Press in 1964. On August 1, 1966, 36 years old at the time, was shot in the arm while covering the mass shooting at the University of Texas at Austin. Heard, who had arrived on scene as a reporter for the Associated Press, was attempting to follow to Texas highway patrol offices across a parking lot when he was wounded by a bullet fired by Charles Whitman. In a 2006 interview with Texas Monthly, Heard recalled, "Just before I reached the curb, I was shot down. I'd forgotten my Marine training, he continued to grant interviews on the anniversary of the shooting, but attempted to distance his professional and personal life from the tragedy. According to his wife, Betsy Heard, "He lived his whole life hoping to get that out of the first paragraph of his obituary."Heard left the Associated Press, but continued to work in journalism and public relations. He worked as a press secretary for Joe Christie, a Democratic U.

S. Senator candidate, during his campaign. Heard wrote for the Texas Lawyer and served as the Texas State Capitol correspondent for the San Antonio Express News. Heard founded Inside a newsletter which covered athletics at the University of Texas, his books included "Dance With Who Brung Us: Quips & Quotes from Darrell Royal," which compiled quotes from Darrell Royal, a former Texas Longhorns football coach. Heard authored "Miracle of the Killer Bees: 12 Senators Who Changed Texas Politics," which focused on twelve Texas state senators who fled Austin in 1979 and went into hiding to stop a bill. Robert Heard died from complications of hip surgery on April 15, 2014, at the age of 84, he was survived by Betsy Heard. A memorial service was planned for his family's June 2014 family reunion in Uvalde County, Texas

Streptomycin

Streptomycin is an antibiotic used to treat a number of bacterial infections. This includes tuberculosis, Mycobacterium avium complex, brucellosis, Burkholderia infection, plague and rat bite fever. For active tuberculosis it is given together with isoniazid and pyrazinamide, it is given by injection into a muscle. Common side effects include feeling like the world is spinning, numbness of the face and rash. Use during pregnancy may result in permanent deafness in the developing baby. Use appears to be safe while breastfeeding, it is not recommended in people with other neuromuscular disorders. Streptomycin is an aminoglycoside, it works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. Streptomycin was discovered in 1943 from Streptomyces griseus, it is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. The World Health Organization classifies it as critically important for human medicine.

The wholesale cost in the developing world is between US$0.38 and $4.39 per day. In the United States, a course of treatment costs more than $200. Infective endocarditis caused by enterococcus when the organism is not sensitive to gentamicin Tuberculosis in combination with other antibiotics. For active tuberculosis it is given together with isoniazid and pyrazinamide, it is not the first-line treatment, except in medically under-served populations where the cost of more expensive treatments is prohibitive. It may be useful in cases. Plague has been treated with it as the first-line treatment; however streptomycin is approved for this purpose only by the U. S. Food and Drug Administration. In veterinary medicine, streptomycin is the first-line antibiotic for use against gram negative bacteria in large animals, it is combined with procaine penicillin for intramuscular injection. Tularemia infections have been treated with streptomycin. Streptomycin is traditionally given intramuscularly, in many nations is only licensed to be administered intramuscularly, though in some regions the drug may be administered intravenously.

Streptomycin is used as a pesticide, to combat the growth of bacteria beyond human applications. Streptomycin controls bacterial diseases of certain fruit, vegetables and ornamental crops. A major use is in the control of fireblight on pear trees; as in medical applications, extensive use can be associated with the development of resistant strains. Streptomycin could be used to control cyanobacterial blooms in ornamental ponds and aquaria. While some antibacterial antibiotics are inhibitory to certain eukaryotes, this seems not to be the case for streptomycin in the case of anti-fungal activity. Streptomycin, in combination with penicillin, is used in a standard antibiotic cocktail to prevent bacterial infection in cell culture; when purifying protein from a biological extract, streptomycin sulfate is sometimes added as a means of removing nucleic acids. Since it binds to ribosomes and precipitates out of solution, it serves as a method for removing rRNA, mRNA, DNA if the extract is from a prokaryote.

Streptomycin can be used clinically to treat tuberculosis in combination with other medications and susceptible strains which cause bacterial endocarditis. The most concerning side effects, as with other aminoglycosides, are kidney toxicity and ear toxicity. Transient or permanent deafness may result; the vestibular portion of cranial nerve VIII can be affected, resulting in tinnitus, ataxia, kidney toxicity, can interfere with diagnosis of kidney malfunction. Common side effects include vertigo, numbness of the face and rash. Fever and rashes may result from persistent use. Use is not recommended during pregnancy. Congenital deafness has been reported in children whose mothers received streptomycin during pregnancy. Use appears to be okay while breastfeeding, it is not recommended in people with myasthenia gravis. Streptomycin is a protein synthesis inhibitor, it binds to the small 16S rRNA of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit.

This leads to codon misreading, eventual inhibition of protein synthesis and death of microbial cells through mechanisms that are still not understood. Speculation on this mechanism indicates that the binding of the molecule to the 30S subunit interferes with 50S subunit association with the mRNA strand; this results in an unstable ribosomal-mRNA complex, leading to a frameshift mutation and defective protein synthesis. Humans have ribosomes which are structurally different from those in bacteria, so the drug does not have this effect in human cells. At low concentrations, streptomycin only inhibits growth of the bacteria by inducing prokaryotic ribosomes to misread mRNA. Streptomycin is an antibiotic that inhibits both Gram-positive and Gram-negative bacteria, is therefore a useful broad-spectrum antibiotic. Streptomycin was first isolated on October 19, 1943, by Albert Schatz, a PhD student in the laboratory of Selman Abraham Waksman at Rutgers University in a research project funded by Merck and Co.

Waksman and his laboratory staff discovered several antibiotics, including actinomycin, streptothricin, grisein, fradicin and candidin. Of these and neomycin found extensive application in the treatment of numerous infectious diseases. Streptomycin was the first antibiotic cure for tubercu