Wilmington station, also known as the Joseph R. Biden, Jr., Railroad Station, is a passenger rail station in Wilmington, Delaware. It serves nine Amtrak train routes and is part of the Northeast Corridor. It also serves SEPTA Regional Rail commuter trains on the Wilmington/Newark Line as well as DART First State local buses and Greyhound Lines intercity buses.

Wilmington is the largest city in the U.S. state of Delaware. The city was built on the site of Fort Christina, the first Swedish settlement in North America. It lies at the confluence of the Christina River and Brandywine Creek, near where the Christina flows into the Delaware River. It is the county seat of New Castle County and one of the major cities in the Delaware Valley metropolitan area. Wilmington was named by Proprietor Thomas Penn after his friend Spencer Compton, Earl of Wilmington, who was prime minister during the reign of George II of Great Britain.