İskenderun, historically known as Alexandretta and Scanderoon, is a municipality and district of Hatay Province, Turkey. Its area is 247 km2, and its population is 251,682 (2022). It is on the Mediterranean coast. Located on an alluvial plain, the city was heavily damaged by powerful earthquakes in February 2023 and subsequent aftershocks, floods and fires.

Hatay Province is the southernmost province and metropolitan municipality of Turkey. Its area is 5,524 km2, and its population is 1,686,043 (2022). It is situated mostly outside Anatolia, along the eastern coast of the Levantine Sea. The province borders Syria to its south and east, the Turkish province of Adana to the northwest, Osmaniye to the north, and Gaziantep to the northeast. It is partially in Çukurova, a large fertile plain along Cilicia. Its administrative capital is Antakya, making it one of the three Turkish provinces not named after its administrative capital or any settlement. The second-largest city is İskenderun. Sovereignty over most of the province remains disputed with neighbouring Syria, which claims that the province had a demographic Arab majority, and was separated from itself against the stipulations of the French Mandate of Syria in the years following Syria's occupation by France after World War I.