The Şehzade Mosque is a 16th-century Ottoman imperial mosque located in the district of Fatih, on the third hill of Istanbul, Turkey. It was commissioned by Suleiman the Magnificent as a memorial to his son Şehzade Mehmed who died in 1543. It is sometimes referred to as the "Prince's Mosque" in English. The mosque was one of the earliest and most important works of architect Mimar Sinan and is one of the signature works of Classical Ottoman architecture.

Şehzade Mehmed was an Ottoman prince, son of Sultan Suleiman the Magnificent and his wife Hürrem Sultan. He served as governor of Manisa.