16 Psyche is a large M-type asteroid, which was discovered by the Italian astronomer Annibale de Gasparis, on 17 March 1852 and named after the Greek goddess Psyche. The prefix "16" signifies that it was the sixteenth minor planet in order of discovery. It is the largest and most massive of the M-type asteroids, and one of the dozen most massive asteroids. It has a mean diameter of approximately 220 kilometers (140 mi) and contains about one percent of the mass of the asteroid belt. It was thought to be the exposed core of a protoplanet, but recent observations cast doubt on that hypothesis. Psyche will be explored by NASA, with a spacecraft of the same name, marking the first time a manmade object will journey to a metallic asteroid, launched on 13 October 2023, with an expected arrival in 2029.

Psyche is the Greek goddess of the soul and often represented as a beautiful woman with butterfly wings. The name Psyche means "soul" in Greek and was commonly referred to as such in Roman mythology as well, though the direct translation is Anima. She was born a mortal woman and eventually granted immortality, with beauty that rivaled even Aphrodite, goddess of love. Psyche is known from the novel The Golden Ass, also known as Metamorphoses, written by the Roman philosopher and orator Apuleius in the 2nd century. In the myth, she was given multiple trials to be with her beloved, Eros, also known as Cupid, god of physical love and desire and son of Aphrodite. The cultural influences of Psyche's story can be depicted in art dating back to the 4th century BCE.