The 2001 Marlboro 500 was a Championship Auto Racing Teams (CART) motor race held on November 4, 2001 at the California Speedway, in Fontana, California. It was the 21st and final round of the 2001 CART season and the fifth annual edition of the Marlboro 500 at California Speedway. The 220-lap race was won by Newman/Haas Racing driver Cristiano da Matta who started from second position. Max Papis finished second for Team Rahal and Forsythe Racing driver Alex Tagliani came in third.

Newman/Haas Racing was an auto racing team that competed in CART, Champ Car, and the IndyCar Series from 1983 to 2011. The team operations were based in Lincolnshire, Illinois. Newman/Haas Racing was formed as a partnership between actor, automotive enthusiast and semi-professional racer Paul Newman and long-time auto racing owner/driver Carl Haas. The duo were competitors in sports car racing during the 1970s and early 1980s. In 1983, they joined forces to enter the ranks of Indy car racing. Newman/Haas was one of the most successful teams in Indy car racing during the 1980s, 1990s, and 2000s. The team won 105 CART/Champ Car races and eight season championships, followed by two race wins in the IRL/IndyCar Series.