The 2011 Crosstown Shootout brawl, nicknamed the Crosstown Punch-Out, was a bench-clearing brawl that took place at the end of the 2011 edition of the Crosstown Shootout college basketball game between the University of Cincinnati Bearcats and the Xavier University Musketeers. The game and brawl took place on December 10, 2011, at Xavier's home arena, the Cintas Center in Cincinnati, Ohio, United States.

A bench-clearing brawl is a form of fighting that occurs in sports, most notably baseball and ice hockey, in which most or all players on both teams leave their dugouts, bullpens, or benches, and charge onto the playing area in order to fight one another or try to break up a fight. Penalties for leaving the bench can range from nothing to severe.