The Alfa Romeo 159 is a car built by Italian marque Alfa Romeo between 2004 and 2011. It is a large family car in the compact-executive market segment with four-door saloon and five-door estate variants. Introduced at the 2005 Geneva Motor Show, as a replacement for the 156, the 159 used the GM/Fiat Premium platform, shared with the Alfa Romeo Brera and Spider as well as the Kamal and Visconti concept cars.

The D-segment is the 4th category of the European segments for passenger cars, and is described as "large cars".