Alien Nation is a science fiction police procedural television series in the Alien Nation franchise. Adapted from the 1988 Alien Nation movie, it stars Gary Graham as Detective Matthew Sikes, a Los Angeles police officer reluctantly working with "Newcomer" alien Sam "George" Francisco, played by Eric Pierpoint. Sikes also has an on again-off again flirtation with a female Newcomer, Cathy Frankel, played by Terri Treas.

Alien Nation is a 1988 American science fiction action film written by Rockne S. O'Bannon and directed by Graham Baker. The ensemble cast features James Caan, Mandy Patinkin, and Terence Stamp. Its initial popularity inaugurated the beginning of the Alien Nation media franchise. The film depicts the assimilation of the "Newcomers", an alien race settling in Los Angeles, much to the initial dismay of the local population. The plot integrates the neo-noir and buddy cop film genres with a science fiction theme, centering on the relationship between a veteran police investigator (Caan) and an extraterrestrial (Patinkin), the first Newcomer detective. The duo probe a criminal underworld while attempting to solve a homicide.