The Allegheny Mountain Range, informally the Alleghenies, is part of the vast Appalachian Mountain Range of the Eastern United States and Canada and posed a significant barrier to land travel in less developed eras. The Allegheny Mountains have a northeast–southwest orientation, running for about 300 miles (480 km) from north-central Pennsylvania, southward through western Maryland and eastern West Virginia.

The Appalachian Mountains, often called the Appalachians, are a mountain range in eastern to northeastern North America. The term "Appalachian" refers to several different regions associated with the mountain range, and its surrounding terrain. The general definition used is one followed by the United States Geological Survey and the Geological Survey of Canada to describe the respective countries' physiographic regions. The U.S. uses the term Appalachian Highlands and Canada uses the term Appalachian Uplands; the Appalachian Mountains are not synonymous with the Appalachian Plateau, which is one of the provinces of the Appalachian Highlands.